Water-quality data have been collected at more than 168 documented sites in the American River basin since early in the century by several universities and State and Federal agencies, but comprehensive water-quality studies of a year or more are few.These data were used collectively in this study to assess the river's present condition.Based on this assessment, the American River was found to be a stream of overall good quality and to be suitable for all beneficial uses as specified by the State of California, even though its natural condition has been altered by man's activities in the basin. Time-trend analyses indicate an increase in specific conductance (dissolved solids), hardness, and alkalinity during the past 20 years in the lower American River near Sacramento downstream from treated effluent and urban runoff sources. Dissolved oxygen and pH have remained steady. Ammonia concentrations in this reach show a close correlation with specific conductance (correlation coefficient = 0.89).Most violations of specific water-quality objectives for the basin have occurred in the lower American River. Water-quality conditions in this reach are expected to improve in late 1982 when sewage-treatment-facility discharges into the river will be discontinued.Extensive water storage and flow regulation on the Middle and South Forks of the American River since the early 1960*s appears to have altered the natural characteristics of these streams.However, insufficient data are available to make a complete assessment. Channel characteristics and beneficial uses have changed markedly in the lower American River since 1955 when Folsom Dam was completed and flows through this reach became regulated.Recreational overuse, improper land use, or poorly managed mining operations are potential sources of future water-quality problems in the upper American River basin.Recreational overuse and increased urban runoff are potential threats to water quality in the lower American River.Proposed monitoring activities include low-flow investigations on the lower American to measure diel variations in water-quality characteristics and studies in the upper basin to determine the impact of increasing recreation and development as well as the effects of mine drainage on the river system.