Water equivalent properties of materials commonly used in proton dosimetry

Vera, Pablo de; Abril, Isabel; García-Molina, Rafael

doi:10.1016/j.apradiso.2013.01.023

Cited by 19 publications

(15 citation statements)

References 29 publications

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“…28,30,39 This approach allows obtaining a reliable excitation and ionisation spectrum for any arbitrary condensed organic material, irrespectively of whether it has been measured or not. The optical ELF is extended to finite momentum transfers ( hk a 0) using the Mermin Energy-Loss Function -Generalised Oscillator Strengths (MELF-GOS) methodology, 38 which has proven to be very successful for handling condensed-phase materials, 32,38,[40][41][42][43] and particularly liquid water. 44,45 The main physical properties of the biomaterials studied in this work (needed for further calculations) are summarised in Table 1.…”

Section: Electronic Excitation and Ionisation Of Biomaterials By Swifmentioning

confidence: 99%

Excitation and ionisation cross-sections in condensed-phase biomaterials by electrons down to very low energy: application to liquid water and genetic building blocks

Vera

Abril

García-Molina

2021

Phys. Chem. Chem. Phys.

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Section: Electronic Excitation and Ionisation Of Biomaterials By Swifmentioning

confidence: 99%

Excitation and ionisation cross-sections in condensed-phase biomaterials by electrons down to very low energy: application to liquid water and genetic building blocks

Vera

Abril

García-Molina

2021

Phys. Chem. Chem. Phys.

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“…The WER is defined as the ratio of the mass thickness of water and the given material (in g/cm 2 ) that leads to the same beam energy loss . WER measurements were performed at OncoRay (Dresden, Germany) at two different proton energies (150, 200 MeV) with a high‐resolution multi‐layer ionization chamber (Giraffe, IBA Dosimetry, Schwarzenbruck, Germany) that measured the shift of the single Bragg peak along the central beam axis after penetrating the respective corset samples.…”

Section: Methodsmentioning

confidence: 99%

Comparison of pancreatic respiratory motion management with three abdominal corsets for particle radiation therapy: Case study

Dolde

Schneider

Stefanowicz

et al. 2019

J Applied Clin Med Phys

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Background and purpose Abdominal organ motion seriously compromises the targeting accuracy for particle therapy in patients with pancreatic adenocarcinoma. This study compares three different abdominal corsets regarding their ability to reduce pancreatic motion and their potential usability in particle therapy. Materials and methods A patient‐individualized polyurethane (PU), a semi‐individualized polyethylene (PE), and a patient‐individualized three‐dimensional‐scan based polyethylene (3D‐PE) corset were manufactured for one healthy volunteer. Time‐resolved volumetric four‐dimensional‐magnetic resonance imaging (4D‐MRI) and single‐slice two‐dimensional (2D) cine‐MRI scans were acquired on two consecutive days to compare free‐breathing motion patterns with and without corsets. The corset material properties, such as thickness variance, material homogeneity in Hounsfield units (HU) on computed tomography (CT) scans, and manufacturing features were compared. The water equivalent ratio (WER) of corset material samples was measured using a multi‐layer ionization chamber for proton energies of 150 and 200 MeV. Results All corsets reduced the pancreatic motion on average by 9.6 mm in inferior–superior and by 3.2 mm in anterior‐posterior direction. With corset, the breathing frequency was approximately doubled and the day‐to‐day motion variations were reduced. The WER measurements showed an average value of 0.993 and 0.956 for the PE and 3DPE corset, respectively, and of 0.298 for the PU corset. The PE and 3DPE corsets showed a constant thickness of 2.8 ± 0.2 and 3.8 ± 0.2 mm, respectively and a homogeneous material composition with a standard deviation (SD) of 31 and 32 HU, respectively. The PU corset showed a variable thickness of 4.2 − 25.6 mm and a heterogeneous structure with air inclusions with an SD of 113 HU. Conclusion Abdominal corsets may be effective devices to reduce pancreatic motion. For particle therapy, PE‐based corsets are preferred over PU‐based corset due to their material homogeneity and constant thickness.

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“…Whereas Newhauser et al purposed to compute WET of gold, stainless steel and titanium by using numerical method [9]. On the other hand, Zhang et al adduce to compute WET of lead, aluminum and PMMA by using simple deterministic method that was derived from Bragg-Kleeman rule (BK) and Bethe-Bloch equation (BB) [10], [11]. Both studies done by Newhauser et al and Zhang et al revealed that the WET and WER calculation is dependent on proton energy intensity, density and thickness of materials.…”

Section: Introductionmentioning

confidence: 99%

MCNPXâ€™S Water Equivalent Thickness Simulation of Material with Different Density via Proton Beam Irradiation

Khattak¹,

Borhana²,

Shafii³

et al. 2018

IJET

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The radiological thickness of materials and beam penetration range is often referred as the water equivalent thickness (WET). In the clinical application of radiotherapy it is mandatory to obtain a WET calculation with high accuracies to ensure the beam that penetrated the human tissues is capable to deliver high dose of radiation into the deep-rooted tumors and kill the malignant cancerous cell without any major damages to the healthy tissues. Nevertheless, the present method of calculation that is available needs either intensive numerical method or approximation techniques with unknown precision. Hence, the purpose of this research is to study the depth of proton beam irradiation penetration range of materials with arbitrary density & elemental composition and modeled the water equivalent thickness (WET) calculation by using the Monte Carlo N Particle Transport Code Extension (MCNPX). There are several type of material with different density that are utilize in this project which are water phantom (ρ =1.0 g cm-3), PMMA (ρ =1.19 g cm-3) aluminum (ρ = 2.70 g cm-3 lead (ρ =11.3g cm-3). The water phantom represent reference material whilst PMMA, Aluminum and Lead each represent low, medium and high density respectively. Based from the result produced in output file, Bragg curves for each material were reproduced, analyzed and compared with the Bragg curve of water phantom. The WET of water phantom was successfully modelled by using MCNPX. Apart from the short computing time, modelling WET via MCNPX was more efficient compare to analytical calculation

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Water equivalent properties of materials commonly used in proton dosimetry

Cited by 19 publications

References 29 publications

Excitation and ionisation cross-sections in condensed-phase biomaterials by electrons down to very low energy: application to liquid water and genetic building blocks

Excitation and ionisation cross-sections in condensed-phase biomaterials by electrons down to very low energy: application to liquid water and genetic building blocks

Comparison of pancreatic respiratory motion management with three abdominal corsets for particle radiation therapy: Case study

MCNPXâ€™S Water Equivalent Thickness Simulation of Material with Different Density via Proton Beam Irradiation

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