Water dispersible 1-one-butyric acid-functionalised multi-walled carbon nanotubes for enzyme immobilisation and glucose sensing

Hua, Mu Yi; Lin, Yu Chen; Tsai, Rung Ywan; Chen, Hsiao‐Chien

doi:10.1039/c2jm15200b

Cited by 22 publications

(7 citation statements)

References 63 publications

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“…One of the effective strategies to enhance the dispersion of CNTs is the surface modication of CNTs via covalent or noncovalent. [19][20][21][22][23][24] In particular, the latter has the advantage of preserving the electronic structure of CNTs and therefore their transport and surface properties. [25][26][27][28] Metal phthalocyanines (MPcs), a well-known class of planar two-dimensional metal complexes with conjugated delocalized 18p-electron systems, have a great versatility due to their electrochemical activity as electrocatalysts.…”

Section: Introductionmentioning

confidence: 99%

A multiwalled carbon nanotube/tetra-β-isoheptyloxyphthalocyanine cobalt(ii) composite with high dispersibility for electrochemical detection of ascorbic acid

et al. 2014

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Section: Introductionmentioning

confidence: 99%

A multiwalled carbon nanotube/tetra-β-isoheptyloxyphthalocyanine cobalt(ii) composite with high dispersibility for electrochemical detection of ascorbic acid

et al. 2014

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“…All previous works reported in the comparison foresee to randomly drop cast CNTs solution onto the working electrode. Glucose oxidase can be directly mix with CNTs, as proposed by Tsai et al [26], or CNTs can even be functionalized with butyric acid, for example, to increase their immobilization prior to deposition, as described in [48]. The last approach reported in Table I obtains the best sensitivity, even if the value is half of what we achieve with our biosensor.…”

Section: A Biosensor Calibration For Glucose and Lactate In Pbsmentioning

confidence: 85%

A Self-Contained System With CNTs-Based Biosensors for Cell Culture Monitoring

Boero

Olivo

Carrara

et al. 2012

IEEE J. Emerg. Sel. Topics Circuits Syst.

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Abstract-Biosensors have been applied to disparate fields, especially for endogenous compounds such as glucose and lactate. The main areas of application are certainly related to medical and diagnostic purposes. However, metabolic monitoring can be also of interest in cell analysis. Cells can be cultivated for several purposes, such as understanding and modeling some biological mechanisms, the development of new drugs and therapies, or in the field of regenerative medicine. All the aforementioned applications require a thorough knowledge of the biological system under study. In this paper, we propose the development of a self-contained system based on electrochemical biosensors for cell culture monitoring. The detection is based on oxidases immobilized onto carbon nanotubes. We also develop an architecture to record the signal generated by the biosensor and transmit it to a remote station by means of a Bluetooth module. We calibrate the system for glucose and lactate detection in phosphate buffer solution. We achieve a sensitivity of 55.5 and a detection limit of 2 for glucose, as well as a sensitivity of 25.0 and a detection limit of 11 for lactate. We finally validate the two biosensors for metabolic monitoring in culture medium and we detect lactate production in neuroblastoma cells after 72 h of cultivation. The integrated system proposed in the present work opens new opportunities towards the development of novel tools for cell analysis.

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“…The absorption band at around 3,416 cm À1 is assigned to -OH group [28], whereas, bands at 1,713 and 1,647 cm À1 are attributed to C=O stretching vibration [29,30]. The peak around 1,563 and 1,214 cm À1 indicate the C=C ring stretching of MWCNTs and -C-O group [31,32], respectively. The FTIR spectrum confirms that MWCNTs are functionalized with hydroxyl and carboxylic groups after chemical modification by mixed acid.…”

Section: Characterization Of Functionalized Mwcntsmentioning

confidence: 96%

Fabrication of ultra-thin polyelectrolyte/carbon nanotube membrane by spray-assisted layer-by-layer technique: characterization and its anti-protein fouling properties for water treatment

Liu

Son

Chakraborty

et al. 2013

Desalination and Water Treatment

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A B S T R A C TPolyethersulfone (PES) membranes are extensively used as ultrafiltration (UF) membrane owing to their superior thermal, mechanical, and chemical stability. However, commercial PES membranes are more prone to fouling, which contributes to severe decline in permeate flux with operation time. To improve the commercial PES UF membrane anti-protein fouling properties, negatively charged functionalized multi-walled carbon nanotube (f-MWCNTs), blended poly(sodium 4-styrenesulfonate) (PSS), and positively charged poly(diallyldimethylammonium chloride) (PDDA) were deposited on 20 kDa PES substrate through sprayassisted layer-by-layer (LbL) technique. Further cross-flow UF tests were conducted with bovine serum albumin (BSA) as model protein. The total flux loss results show that surfacemodified PES membranes are less susceptible to protein fouling by one-hour BSA filtration. Moreover, flux recovery ratios show that 20-min de-ionized (DI) water flushing is effective to restore water flux of the prepared membrane without aggressive chemical cleaning. Based on the experimental results, the excellent anti-fouling properties render the prepared membranes suitable for recycling utilization.

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Water dispersible 1-one-butyric acid-functionalised multi-walled carbon nanotubes for enzyme immobilisation and glucose sensing

Cited by 22 publications

References 63 publications

A multiwalled carbon nanotube/tetra-β-isoheptyloxyphthalocyanine cobalt(ii) composite with high dispersibility for electrochemical detection of ascorbic acid

A multiwalled carbon nanotube/tetra-β-isoheptyloxyphthalocyanine cobalt(ii) composite with high dispersibility for electrochemical detection of ascorbic acid

A Self-Contained System With CNTs-Based Biosensors for Cell Culture Monitoring

Fabrication of ultra-thin polyelectrolyte/carbon nanotube membrane by spray-assisted layer-by-layer technique: characterization and its anti-protein fouling properties for water treatment

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