It is well known that low-frequency pulsed electromagnetic fields are able to stimulate the restoration of damaged neural contacts. Despite the fact that this effect is widely used by physicians, the physical basis of such an action of lowfrequency pulsed electromagnetic fields remains unknown. In this aspect, it is of interest that the drying of chloride solutions prepared in negatively charged water is accompanied by the formation of tree-shaped crystals, i.e. their arborization. Based on this, it was suggested that low-frequency pulsed electromagnetic fields cause negative electrification of aqueous solutions of chlorides, which are the main inorganic anions of nerve tissues, and, as a result, axonal arborization of neurons. During the experimental verification of such an assumption, the formation of tree-like crystals in drying solutions of chlorides was detected, through which weak constant and low-frequency pulsed electric currents were previously passed. This made it possible to suggest an explanation of the nature of axonal arborization of neurons, including those damaged, which is observed under the influence of low-frequency pulsed electromagnetic fields in vivo. Since chlorides are the main inorganic anions of blood, it was also proposed to explain the formation of new capillaries under the action of low-frequency pulsed electromagnetic fields. After a more detailed analysis, it was suggested that this kind of negative electrization of aqueous solutions of chlorides was due to free hydrogen atoms, which are the products of water electrolysis. However, it was suggested that oxygen atoms, which also appear during the electrolysis of water, are bound by chloride anions to form hypochlorite anions. Thus, such oxygen atoms are not able to cause a positive electrification of aqueous media in which there are electrical currents, including currents, caused by low-frequency pulsed electromagnetic fields. Thus, the importance of chlorine anions for regenerative processes, in general, was justified. However, it has been suggested that these hypochlorite anions can stimulate cell proliferation, as well as other active forms of oxygen. Thus, an understandable physicochemical basis of the therapeutic effects of low-frequency pulsed electromagnetic fields was proposed and partially experimentally established.