1985
DOI: 10.1097/00007632-198501000-00011
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Water and Electrolyte Content of Human Intervertebral Discs Under Variable Load

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Cited by 136 publications
(77 citation statements)
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“…It has been shown that sustained compression on the discs, as occurs during sitting, hampers¯uid¯ow into the disc (Kingma et al 2000), which consequently aOE ects disc nutrition adversely (Maroudas et al 1975, Holm et al 1981. Reducing the compression force acting on the spine (Kraemer et al 1985) or imposing movements (Deursen et al 2001) may both reduce or reverse the¯ow of¯uid from the disc. This would result in reduced spinal shrinkage or enhanced recovery of shrinkage, since spinal shrinkage is in part accounted for by¯uid¯ow from the intervertebral discs (Roberts et al 1998).…”
Section: Introductionmentioning
confidence: 99%
“…It has been shown that sustained compression on the discs, as occurs during sitting, hampers¯uid¯ow into the disc (Kingma et al 2000), which consequently aOE ects disc nutrition adversely (Maroudas et al 1975, Holm et al 1981. Reducing the compression force acting on the spine (Kraemer et al 1985) or imposing movements (Deursen et al 2001) may both reduce or reverse the¯ow of¯uid from the disc. This would result in reduced spinal shrinkage or enhanced recovery of shrinkage, since spinal shrinkage is in part accounted for by¯uid¯ow from the intervertebral discs (Roberts et al 1998).…”
Section: Introductionmentioning
confidence: 99%
“…Under load, the disc loses water, with an increasing concentration of sodium and potassium ions. The increase in electrolyte concentration acts as an osmotic reabsorption force and with load reduction disc volume and height is restored [13]. Irreversible loss of disc height may be found with the reduction of disc tissue volume, for example in cases of disc herniation [21].…”
Section: Introductionmentioning
confidence: 99%
“…The opposite occurs when the load is released, i. e. an influx of fluid to the disc and an increase in disc height. Kraemer et al (1985) showed that a disc after a long period of loading and water loss gets a higher concentration of electrolytes. This increases its osmotic absorption force and also aids holding back the remaining yater.…”
Section: Properties Of the Intervertebral Discmentioning
confidence: 99%