Warts and molluscum contagiosum

Williams, Lynn R.; Webster, Guy F.

doi:10.1016/0738-081x(91)90121-z

Cited by 16 publications

(4 citation statements)

References 61 publications

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“…The physical modalities of treatment are generally regarded as most effective. Curettage and cryotherapy are among the most widely used ( 4). Alternatively, chemical agents such as podophyllin, tretinoin, cantharidin, trichloroacetic acid, silver nitrate, phenol, salicylic acid, and tincture of iodine have been used with variable results ( 5, 6).…”

Section: Discussionmentioning

confidence: 99%

Treatment of Molluscum Contagiosum with Potassium Hydroxide: A Clinical Approach in 35 Children

Romiti

Ribeiro

Grinblat

et al. 1999

Pediatric Dermatology

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Potassium hydroxide (KOH) is a strong alkali that has long been known to digest proteins, lipids, and most other epithelial debris of skin scrapings to identify fungal infections. To our knowledge, KOH has never been used for the treatment of molluscum contagiosum (MC). We evaluated 35 children with MC for the clinical effectiveness of treatment with topical 10% KOH aqueous solution. The solution was applied by the parents of affected children, twice daily, on each MC lesion. The therapy was continued until all lesions underwent inflammation and superficial ulceration. Thirty-two of 35 patients achieved complete clinical cure after a mean treatment period of 30 days. Three children discontinued treatment: two reported severe stinging of the lesions and refused further applications; the other, with giant MC lesions, developed a secondary infection with prolonged treatment. Therapy with KOH was found to be effective and safe in the treatment of MC in children.

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Section: Discussionmentioning

confidence: 99%

Treatment of Molluscum Contagiosum with Potassium Hydroxide: A Clinical Approach in 35 Children

Romiti

Ribeiro

Grinblat

et al. 1999

Pediatric Dermatology

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“…Molluscum contagiosum is a common viral infection in children for which parents often seek treatment. A wide variety of physical and chemical modalities have been employed to treat these lesions but there is no universally agreed “gold standard,” and treatment is often limited by side effects (3–13). Potassium hydroxide is an alkali known to dissolve keratin, hence it is routinely used to identify fungal elements in skin scrapings.…”

Section: Discussionmentioning

confidence: 99%

Double‐Blind, Randomized, Placebo‐Controlled Trial of the Use of Topical 10% Potassium Hydroxide Solution in the Treatment of Molluscum Contagiosum

Short

Fuller

Higgins

2006

Pediatric Dermatology

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Molluscum contagiosum is a common viral infection of the skin that frequently affects children. Lesions take between 6 and 18 months to resolve spontaneously and are a source of great embarrassment to both caretakers and children, often affecting attendance at school and limiting social activity. Treatment options to date have been poorly tolerated by children but recent studies have suggested that potassium hydroxide may be beneficial. This double-blind, randomized, placebo-controlled study compared 10% potassium hydroxide with placebo (normal saline). Twenty patients, aged 2 to 12 years, were recruited. Parents applied a solution twice daily to lesional skin until signs of inflammation appeared. Children were examined by the same observer on days 0, 15, 30, 60, and 90. Seventy percent of children receiving topical potassium hydroxide cleared, compared with 20% in the placebo group. Further dosing studies are required to identify whether weaker concentrations of potassium hydroxide are as efficacious, with less irritancy.

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“…It is caused by one of three poxviruses (MCV I, MCV II, MCV III) (26), which are large double-stranded DNA viruses that replicate within the cytoplasm of keratinocytes. Within the host cell, the virion colony is encased and isolated Management of viral infections with imiquimod 5% cream 13 in a protective sac, thereby preventing activation of the host's cell-mediated immune response (27,28). Transmission of the virus is facilitated by mechanical trauma (29).…”

Section: Imiquimod For the Treatment Of Molluscum Contagiosummentioning

confidence: 99%

3. Successful Management of Viral Infections and Other Dermatoses with Imiquimod 5% Cream

Berman¹,

Hengge²,

Barton³

2003

Acta Derm Venereol

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Warts and molluscum contagiosum

Cited by 16 publications

References 61 publications

Treatment of Molluscum Contagiosum with Potassium Hydroxide: A Clinical Approach in 35 Children

Treatment of Molluscum Contagiosum with Potassium Hydroxide: A Clinical Approach in 35 Children

Double‐Blind, Randomized, Placebo‐Controlled Trial of the Use of Topical 10% Potassium Hydroxide Solution in the Treatment of Molluscum Contagiosum

3. Successful Management of Viral Infections and Other Dermatoses with Imiquimod 5% Cream

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