Warts

Rulison, R. H.

doi:10.1001/archderm.1942.01500130069006

Cited by 36 publications

(5 citation statements)

References 5 publications

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“…However, the infrequency of genital warts in dermatological, surgical, and gynae-I FIG. 15 Verruca vulgaris of the penis (A). Notice close morphological resemblance to common warts in cubital fossa of same patient (B) cological practice has been noted several times (Ebergenyi, 1939;Speiser, 1942); Rulison (1942) stated that the diagnosis of 'condyloma acuminatum' was made only 32 times in 250,000 patients who attended the New York Skin and Cancer Hospital between 1925 and 1934. On the other hand, genital warts are often seen in venereal disease clinics, so that the age of incidence recorded here is probably the true one, and the resemblance to gonorrhoea significant.…”

Section: Discussionmentioning

confidence: 80%

Natural history of genital warts.

Oriel¹

1971

Sexually Transmitted Infections

257

172

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Section: Discussionmentioning

confidence: 80%

Natural history of genital warts.

Oriel¹

1971

Sexually Transmitted Infections

257

172

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“…The recurrence rate of warts is known to be high; Rulison (1942) estimated it to be about 5% for common warts, occurring within 3-4 months. Many hold the view that an assessment ofthe recurrence rate should be included in all treatment trials.…”

Section: The Level Of Cure For Sal Paint In the Treatment Of Mosaic Wmentioning

confidence: 99%

An assessment of methods of treating viral warts by comparative treatment trials based on a standard design

1976

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A series of eleven comparative wart treatment trials undertaken between 1969 and 1975 and involving 1802 patients is described. A method of coding provided groups of patients matched for age, type, number and duration of warts, within which treatments could be randomized. The variation in response to treatment was shown to be influenced significantly by these factors and the level of cure to depend on the proportions of the various response groups within the population under consideration. These proportions were found to vary geographically and at different periods. In all the trials the results were assessed at 12 weeks. In the treatment of hand warts, the percentage cure of patients treated with liquid nitrogen fell significantly from 75 to 40% when the interval between freezings was increased from 3 to 4 weeks. The average number of freezings required for a cure was 3-1 amongst all patients cured by 6 or less freezings at intervals of 2 or 3 weeks. In a two-centre trial there was no significant difference between the percentage cure of patients with hand warts treated with liquid nitrogen (69%) and of those applying a paint containing salicylic and lactic acids (SAL) (67%). Patients receiving both treatments concurrently did better (78%) but the difference was not found to be statistically significant. In the treatment of simple plantar warts the percentage cure for the SAL paint (84%) was found to compare favourably with that for a podophyllin treatment (81%). Only one of the patients cured by the paint in that trial was found to have had a recurrence after 6 months. The paint was found to be satisfactory for use under general practice conditions. Additions to the formula did not alter its effectiveness. In the treatment of mosaic plantar warts the overall percentage cure for the SAL paint in a series of comparative trials (1969-75) was 45%. In these trials it was compared directly with one or more other preparations. No differences were found between its efficacy and that of 10% buffered gluteraldehyde (47%), 40% benzalkonium chloride dibromide (Callusolve 40) (30%) and 5% 5-fluorouracil in dimethyl sulphoxide (53%). Only 25% of thirty-six patients treated with 5% idoxuridine in dimethylsulphoxide were cured. Throughout the trials approximately 30% of patients with hand warts, 20% of those with simple plantar warts and 50% of those with mosaic plantar warts were found to be resistant to treatment. The adoption of treatment with SAL paint for hand warts and simple plantar warts by the general practitioners in the Edinburgh area has proved satisfactory. Only resistant cases are now referred to hospital and these can be treated within a few weeks instead of 4-5 months as was the case in 1969.

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“…The studies of Rulison (1942) and Massing and Epstein (1963) still serve as the most comprehensive data sets available concerning the natural history of untreated warts. In Rulison's study (N = 921), wart duration ranged from 1 month to 28 years.…”

Section: Methodological Cons Ideration Smentioning

confidence: 99%

“…Traditional medical interventions appear to be relatively ineffective in treating warts. Of 160 patients who sought treatment in Rulison's (1942) study, no more than 55% experienced successful results, and reoccurrences following more radical treatment (e.g., surgery) were not uncommon.…”

Section: Clinical Applicationsmentioning

confidence: 97%

Psychological treatment of warts.

DuBreuil¹,

Spaños²

1993

Handbook of Clinical Hypnosis.

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Numerous case studies and several experiments have indicated that suggestive procedures may be effective in treating a variety of dermatological disorders, including congenital ichthyosiform erythrodermia of Brocq (fish skin disease; Mason, 1955; Wink, 1961), psoriasis (Frankel & Misch, 1973, genital herpes (Longo, Clum, &Yaeger, 1988), and warts (e.g., Couper &Davies, 1952;Obermayer & Greenson, 1949). Some dermatological disorders, such as fish skin disease, are so rare as to preclude multisubject experimental studies regarding the effects of psychological treatment. Other disorders, like psoriasis, are relatively common. Nevertheless, controlled experiments assessing the effects of psychological treatments for this disorder are nonexistent. One experiment (Longo et al., 1988) assessed the effects of psychological treatment on the frequency and severity of genital herpes outbreaks. In this case, however, verbal report was the only criterion for assessing the severity and frequency of outbreaks, and, consequently, the extent to which reporting biases influenced the validity of the results remains impossible to determine.In contrast with other skin disorders, warts have been studied fairly extensively. Warts are a relatively common disorder (Lynch, 1982), and 62 3

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Warts

Cited by 36 publications

References 5 publications

Natural history of genital warts.

Natural history of genital warts.

An assessment of methods of treating viral warts by comparative treatment trials based on a standard design

Psychological treatment of warts.

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