Warming of infusion syringes caused by electronic syringe pumps

Syringe infusion pumps (SIPs) led to major advances in infusion therapy and were gradually applied to the transfusion of packed red blood cells (RBCs), raising questions about possible cell damage. The objectives of this study were to determine levels of hematocrit (%), total hemoglobin (g/dL), free hemoglobin (g/dL), lactate dehydrogenase (units/L), potassium (mmol/L), the degree of hemolysis (%) of RBCs infused by an SIP, and to investigate the influence of the infusion rate. The experimental study comprised 14 RBCs, 3 SIPs, and infusion rates of 5, 10, and 20 mL/h. The results showed total hemoglobin reduction (P = .003), and increased free hemoglobin and hemolysis (P <.001) were identified. The conclusion reached was that RBCs presented changes in free hemoglobin and degree of hemolysis.

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Levels of Hemolysis Markers in Erythrocyte Concentrates Administered Using a Syringe Infusion Pump

Gannam

Belela-Anacleto

Kusahara

et al. 2018

Journal of Infusion Nursing

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Warming of infusion syringes caused by electronic syringe pumps

Abstract: Infusion solutions can be significantly warmed by syringe pumps. This has potential impact on bacterial growth and the stability of drug solutions and blood products infused, as well as on the susceptibility to hydrostatic pressure changes within the infusion syringe.

Cited by 1 publication

References 15 publications

Levels of Hemolysis Markers in Erythrocyte Concentrates Administered Using a Syringe Infusion Pump

Levels of Hemolysis Markers in Erythrocyte Concentrates Administered Using a Syringe Infusion Pump

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