The use of topological invariants to describe geometric phases of quantum matter has become an essential tool in modern solid state physics. The first instance of this paradigmatic trend can be traced to the study of the quantum Hall effect, in which the Chern number underlies the quantization of the transverse Hall conductivity. More recently, in the framework of time-reversal symmetric topological insulators and quantum spin Hall systems, a new topological classification has been proposed by Fu, Kane and Mele, where the label takes value in Z 2 . We illustrate how both the Chern number c ∈ Z and the Fu-Kane-Mele invariant δ ∈ Z 2 of 2-dimensional topological insulators can be characterized as topological obstructions. Indeed, c quantifies the obstruction to the existence of a frame of Bloch states for the crystal which is both continuous and periodic with respect to the crystal momentum. Instead, δ measures the possibility to impose a further time-reversal symmetry constraint on the Bloch frame. Key words: Topological insulators, quantum Hall effect, quantum spin Hall effect, Chern numbers, Fu-Kane-Mele invariants, obstruction theory.Later theoretical investigations showed that a topological phenomenon underlies this quantization: the integer n in the above formula was shown to be the first Chern number of a vector bundle, naturally associated to the quantum system [27,1,2].The only role played by the magnetic field in quantum Hall systems is that of breaking time-reversal symmetry: if the system were time-reversal symmetric, then the Hall conductivity would vanish, and the system would remain in an insulating state. This fact was clarified by Haldane [14], who showed that non-trivial topological phases can be displayed also in absence of a magnetic field, thus initiating the field of Chern insulators [3,5]. Picking up on the work by Haldane, Fu, Kane and Mele [18,11,12] later introduced a model which still displays a topological phase even if time-reversal symmetry is preveserved, and is by now recognized as a milestone in the history of topological insulators. The phenomenon that the model proposed to illustrate is that of the quantum spin Hall effect, which differs from the quantum Hall effect in that the external magnetic field is replaced by spin-orbit interactions (exactly to preserve time-reversal symmetry), and spin rather than charge currents flow on the boundary of the sample. From the point of view of topological phases, the peculiarity of this phenomenon is that, contrary to what happens for Chern and quantum Hall insulators, one can only distinguish between the trivial (insulating) and non-trivial (quantum spin Hall) phase: the label is then assigned by a Z 2 -valued topological index. Giving a full account of the geometric nature of this invariant has been a primary objective for mathematical physicists in the last decade, and a plethora of mathematical tools has been used in this endeavour, ranging from K-theory to homotopy theory, from functional analysis to noncommutative geometry, from equivar...