Wann und wie muss ein Schilddrüsenknoten abgeklärt werden?

Procopiou, Michel

doi:10.1024/0040-5930/a000166

Cited by 4 publications

(3 citation statements)

References 8 publications

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“…Undiagnosed thyroid disorders (morphological or functional) are found in up to 75% of the population [4,5]. Thyroid nodules are detected in 30 to 68% [4,6,7], most of them as incidental findings [2,8,9]. Some studies observed an increasing prevalence of thyroid nodules, most likely due to an improved resolution of thyroid ultrasound devices, which are now able to detect thyroid nodules of 2 to 3 mm [2,6,7].…”

Section: Introductionmentioning

confidence: 99%

Frequency of thyroid function tests and examinations in participants of a population-based study

Kiel

Ittermann

Völzke

et al. 2020

BMC Health Serv Res

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Background: Thyroid disorders are common in the adult German population. Little is known about guideline implementation in clinical practice and the prevalence of diagnostic procedures in ambulatory care. The study aims to investigate the use of thyroid hormone measurements, thyroid ultrasound, thyroid scintiscan and associated costs in ambulatory care at population level.Methods: Data were derived from two independent population-based cohorts of the Study of Health In Pomerania (SHIP). Ambulatory billing data from the Association of Statutory Health Insurance Physicians Mecklenburg-Vorpommern were individually linked for the period 2002-2016 with SHIP data. The main outcomes were the frequency of outpatient ultrasound, scintiscan, serum TSH level measurement, free triiodothyronine (fT3) and free thyroxine (fT4) measurement, TSH-receptor-antibodies and microsomal antibodies measurement within 1 year and 3 years prior to the study entrance of the participants. Multinomial logistic regression models were used to assess the association of age, sex, thyroid medication intake and Charlson-Comorbidity-Index with frequency of TSH measurements and ultrasound examinations.Results: A total of 5552 participants (47% male, median age 55) were included in the analysis. 25% (1409/5552) had a diagnosed thyroid disorder or treatment, 40% (2191/5552) had clinical findings based on ultrasound or laboratory testing in SHIP only and 35% (1952/5552) neither a coded thyroid disorder or clinical finding nor thyroid medication. In the total study population 30% (1626/5552) received at least one TSH measurement, 6.8% (378/5552) at least one thyroid ultrasound and 2.6% (146/5552) at least one scintiscan within the past year before the study examination. Tests were performed more frequently in patients with thyroid medication and coded thyroid disorders. Hence, this group caused the highest expenditures. Conclusions:Given the high prevalence of thyroid disorders, diagnostic and monitoring tests should be used rationally with regard to costs. TSH levels should be monitored regularly in patients on thyroid medication. A consensus on monitoring frequency and iteration of monitoring of morphological thyroid disorders with TSH and ultrasound and specific guideline recommendations are needed. Trial registration: Versorgungsforschung Deutschland (VfD_17_003880).

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Section: Introductionmentioning

confidence: 99%

Frequency of thyroid function tests and examinations in participants of a population-based study

Kiel

Ittermann

Völzke

et al. 2020

BMC Health Serv Res

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“…In der Praxis werden diese Knoten i. d. R. einmal jährlich kontrolliert, ohne dass es dafür einen belegten Nutzen gibt. Regelmäßige Kontrollen können jedoch bei betroffenen Per-sonen auch Verunsicherung und Ängste auslösen, sodass hier eine pragmatische Lösung notwendig ist [24].…”

Section: Monitoringunclassified

Zufallsbefund Schilddrüsenknoten: Bewertung des Krebsrisikos

Kiel¹,

Angelow²

2021

Allgemeinmedizin up2date

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“…Thyroid nodules refer to scattered lesions caused by localized abnormal growth of thyroid cells, and they are a common disorder of the endocrine system [1] . Over 95% of thyroid nodules are benign, and surgical treatment is generally unnecessary [2] . In the absence of thyroid dysfunction, most patients do not exhibit significant clinical symptoms.…”

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confidence: 99%

Meta-analysis of the Incidence of Thyroid Nodules in China and a Survey on the Incidence of Thyroid Nodules in Fuyu County, Heilongjiang Province

Xie,

Liu,

et al. 2023

Trends in Oncology

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Objective: This study aimed to understand the incidence of thyroid nodules in China through a metaanalysis and analyze the epidemiology of thyroid nodules in the adult population of Fuyu County, Heilongjiang Province, providing assistance for clinical diagnosis and treatment. Methods: We searched the China National Knowledge Infrastructure (CNKI), Wanfang Data, and VIP databases to collect literature published from 2010 to 2021 on the incidence of thyroid nodules in China. Stata 15.1 software was used to estimate the prevalence, and subgroup analyses were performed for age, gender, and blood pressure factors. We also analyzed the health examination data of 10,911 adults in Fuyu County from 2016 to 2020, gathered during the Harbin Medical University Cancer Hospital's precision poverty alleviation program "Healthy Prosperity Tour." The prevalence of thyroid nodules in the study population was calculated based on thyroid ultrasound results, and statistical analysis was conducted using SPSS 26.0 software. Results: The meta-analysis included a total of 330 studies. The results showed that the overall incidence of thyroid nodules in China was 34.7% [95% CI (32.9%, 36.5%)]. The incidence in males was 30.1% [95% CI (28.2%, 32.1%)], and in females, it was 40.1% [95% CI (27.8%, 42.4%)]. The total incidence of thyroid nodules in the three northeastern provinces (Heilongjiang, Jilin, and Liaoning) was 34.8% [95% CI (23.3%, 46.2%)], with a male incidence of 33.2% and a female incidence of 44.5%. The survey in Fuyu County revealed an overall incidence of 48.8% (5322/10911) for thyroid nodules. The female incidence was 53.3% (3937/7390), significantly higher than the male incidence of 39.3% (1385/3521), with statistically significant differences. Logistic regression analysis showed that the final factors included in the regression model were gender and age (P < 0.05), while blood pressure had no significant impact on thyroid nodules (P > 0.05). Discussion: The incidence of thyroid nodules in China is relatively high, 1. Methods

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Wann und wie muss ein Schilddrüsenknoten abgeklärt werden?

Cited by 4 publications

References 8 publications

Frequency of thyroid function tests and examinations in participants of a population-based study

Frequency of thyroid function tests and examinations in participants of a population-based study

Zufallsbefund Schilddrüsenknoten: Bewertung des Krebsrisikos

Meta-analysis of the Incidence of Thyroid Nodules in China and a Survey on the Incidence of Thyroid Nodules in Fuyu County, Heilongjiang Province

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