The Kambélé auriferous pluton in south-eastern Cameroon is within the Central African Fold Belt (CAFB). New zircon LA-ICP-MS U-Pb ages, REEs patterns, zircon Ce 4+ / Ce 3+ ratios, and Ti-in-zircon thermometry, have been used to decipher the timing of mineralisation, redox conditions and emplacement temperature of the pluton. Cathodoluminescence images of 12 representative zircon grains from the Kambélé pluton reveal two types of zircon grains: type 1 grains are characterized by dark cores, serrated margins and poorly defined zonation; type 2 grains are euhedral to subhedral, elongated, with core to rim zonation and with darker rims indicative of a pristine magmatic source. The zircon grains are depleted in light rare earth elements. Chondrite-normalised REE patterns show undefined Ce anomalies and negative Eu anomalies indicating moderately oxidised to reduced conditions. Zircon U-Pb age of the granitoid is constrained to Neoproterozoic with a mean age of 589±36 Ma indicating gold mineralisation during the Pan African orogeny. Crystallization temperatures range from 525-1033°C with a mean temperature of ~712°C, concomitant with granitoid emplacement temperatures within the Adamawa Yadé Domain of the CAFB.