Wait-time for hysterectomy and survival of women with early-stage cervical cancer: A clinical implication during the coronavirus pandemic

Abstract

Examined effect of long wait-time (≥8 weeks) for surgical treatment on survival of women with early-stage cervical cancer.• Long surgery wait-time was not associated with short-term disease recurrence of women with early-stage cervical cancer.• Systematic review suggests that surgery wait-time for up to 8 weeks may have limited/modest effect on disease recurrence.

Cancer management during the COVID-19 pandemic: Choosing between the devil and the deep blue sea

“…Several articles have provided insight into how practitioners should approach this difficult dilemma accordingly to each cancer histology. Suggestions and guidelines are available for head and neck, sino-nasal, spinal, breast, upper tract urothelial, cervical, penile, testicular, pancreatic, kidney, gastric, colorectal, skin, adrenal, liver, prostate, ovarian, endometrial, bladder and endocrine cancer ( Cohen et al, 2020 ; Baumann et al, 2020 ; Werner et al, 2020 ; Tarantola et al, 2013 ; Catanese et al, 2020 ; Vecchione et al, 2020 ; Turri-Zanoni et al, 2020 ; de C. Zequi and Abreu, 2020 ; Gravas et al, 2020 ; O’Leary et al, 2020 ; Casco et al, 2020 ; Katims et al, 2020 ; Berjano et al, 2020 ; Kapuria et al, 2020 ; P. March 25 and 2020, 2021 ; Tachibana et al, 2020 ; Loveday et al, 2020 ; Jones et al, 2020 ; Villani et al, 2020 ; Fligor et al, 2020 ; Sanchez et al, 2020 ; Wallis et al, 2020 ; Topf et al, 2020 ; Matsuo et al, 2020 ; Colombo et al, 2020 ; Campi et al, 2020 ; Raghavan et al, 2020 ).…”

Association between hysterectomy wait-time and all-cause mortality for micro-invasive cervical cancer: treatment implications during the coronavirus pandemic

“…As there are few data to describe the survival effect of delay in hysterectomy in cervical cancer [ 4 , 6 ], our analysis of stage IA tumors provides valuable information in the management of women with early-stage cervical cancer and suggests that recommendations by recent expert panels to postpone hysterectomy for 6–8 weeks among patients with early-stage cervical cancer in centers or regions with a high burden of COVID-19 disease are reasonable for stage IA disease and do not adversely impact survival [ 7 ].…”

Effect of delay in surgical therapy for early-stage cervical cancer: An implication in the coronavirus pandemic

“…Patients with early-stage cervical cancer are commonly treated with hysterectomy, and in hospitals with a high burden of COVID-19, postponing surgery for 6e8 weeks has been suggested by expert panels [8]. There is little data to describe the effect of delay in treatment on survival for women with early-stage cervical cancer [16]. We therefore examined the association between hysterectomy wait-time and oncologic outcomes for early-stage cervical cancer.…”