Waist circumference, visceral abdominal fat thickness and three components of metabolic syndrome

Kawada, Tomoyuki; Andou, Takeshi; Fukumitsu, Masayuki

doi:10.1016/j.dsx.2015.08.013

Cited by 11 publications

(10 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Obesity, sometimes defined as the amount of visceral fat, is associated with CVD 1,2. Waist circumference (WC) is an indicator of obesity that reflects abdominal visceral fat and is easy to measure 1–3. On the other hand, computed tomography (CT) is expensive and carries the disadvantage of risk, including radiation exposure.…”

Section: Introductionmentioning

confidence: 99%

The Correlation between the Ratio of Visceral Fat Area to Subcutaneous Fat Area on Computed Tomography and Lipid Accumulation Product as Indexes of Cardiovascular Risk

Kwon

Han

2019

JOMES

View full text Add to dashboard Cite

BackgroundVisceral obesity and cardiovascular disease are closely related. Research on relevant indexes of cardiovascular disease is particularly important. One of these indexes is lipid accumulation product (LAP). However, the relationship between LAP and the ratio of visceral fat area to subcutaneous fat area (V/S ratio) remains unclear.MethodsIndividuals who visited the university hospital health promotion center and underwent abdominal computed tomography (CT) were included in the study. We analyzed the V/S ratio obtained using CT with cardiovascular factors and indexes. Standardized coefficients were used to obtain uniform units of all independent variables, and the relationship between LAP and V/S ratio was determined using multiple logistic regression analysis.ResultsA positive correlation between the V/S ratio and LAP was observed even after adjustment for age, smoking history, alcohol drinking history, and exercise (P<0.001). The highest quartile of LAP was independently associated with abdominal obesity (odds ratio [OR], 1.160; 95% confidence interval [CI], 1.093–1.232) and visceral fat ≥100 cm2 (OR, 1.018; 95% CI, 1.010–1.026), but not with hypertension or diabetes.ConclusionLAP is closely related to the V/S ratio and can be used to predict the condition of visceral fat tissue.

show abstract

Section: Introductionmentioning

confidence: 99%

The Correlation between the Ratio of Visceral Fat Area to Subcutaneous Fat Area on Computed Tomography and Lipid Accumulation Product as Indexes of Cardiovascular Risk

Kwon

Han

2019

JOMES

View full text Add to dashboard Cite

show abstract

“…By contrast, the enlarged WC frequently predicted increased fat mass accumulation, which could adequately reflect the real burden of central obesity [ 47 , 48 ]. Accordingly, WC showed superior predicting value for predicting insulin resistance and diagnosis of adult MetS when compared with BMI [ 2 , 8 , 49 , 50 ]. Besides, the WC was not only significantly associated with the development of complications under the MetS [ 51 , 52 ] but also linked to the mortality risk in the general population [ 48 , 53 – 56 ].…”

Section: Discussionmentioning

confidence: 99%

Association between triglyceride-glucose related indices with the all-cause and cause-specific mortality among the population with metabolic syndrome

Wei,

Min,

Song

et al. 2024

Cardiovasc Diabetol

View full text Add to dashboard Cite

Background Triglyceride-glucose (TyG) index has been determined to play a role in the onset of metabolic syndrome (MetS). Whether the TyG index and TyG with the combination of obesity indicators are associated with the clinical outcomes of the MetS population remains unknown. Method Participants were extracted from multiple cycles of the National Health and Nutrition Examination Survey (NHANES) between 1999 and 2018 years. Three indicators were constructed including TyG index, TyG combining with waist circumference (TyG-WC), and TyG combining with waist-to-height ratio (TyG-WHtR). The MetS was defined according to the National Cholesterol Education Program (NCPE) Adult Treatment Panel III. Kaplan-Meier (KM) curves, restricted cubic splines (RCS), and the Cox proportional hazard model were used to evaluate the associations between TyG-related indices and mortality of the MetS population. The sensitive analyses were performed to check the robustness of the main findings. Results There were 10,734 participants with MetS included in this study, with 5,570 females and 5,164 males. The median age of the study population was 59 years old. The multivariate Cox regression analyses showed high levels of TyG-related indices were significantly associated with the all-cause mortality of MetS population [TyG index: adjustedhazard ratio (aHR): 1.36, 95%confidence interval (CI): 1.18–1.56, p < 0.001; TyG-WHtR index: aHR = 1.29, 95%CI: 1.13–1.47, p < 0.001]. Meanwhile, the TyG-WC and TyG-WHtR index were associated with cardiovascular mortality of the MetS population (TyG-WC: aHR = 1.45, 95%CI: 1.13–1.85, p = 0.004; TyG-WHtR: aHR = 1.50 95%CI: 1.17–1.92, p = 0.002). Three TyG-related indices showed consistent significant correlations with diabetes mortality (TyG: aHR = 4.06, 95%CI: 2.81–5.87, p < 0.001; TyG-WC: aHR = 2.55, 95%CI: 1.82–3.58, p < 0.001; TyG-WHtR: aHR = 2.53 95%CI: 1.81–3.54, p < 0.001). The RCS curves showed a non-linear trend between TyG and TyG-WC indices with all-cause mortality (p for nonlinearity = 0.004 and 0.001, respectively). The sensitive analyses supported the positive correlations between TyG-related indices with mortality of the MetS population. Conclusion Our study highlights the clinical value of TyG-related indices in predicting the survival of the MetS population. TyG-related indices would be the surrogate biomarkers for the follow-up of the MetS population.

show abstract

“…The importance of abdominal visceral fat in maintaining health, makes accurate visceral fat measurement crucial. Among the methods for measuring abdominal visceral fat, waist circumference (WC) is an easy to measure indicator of obesity [ 32 , 33 ]. While, measurement of visceral fat and subcutaneous fat by computed tomography (CT) can more accurately reflect the amount of visceral fat and risks of various metabolic diseases and cardiovascular disease, it is expensive and risks radiation exposure [ 34 , 35 ].…”

Section: Discussionmentioning

confidence: 99%

Anti-obesity effect of Neoagaro-oligosaccharides with overweight and obese subjects: a 16-week, randomized, double-blind, placebo-controlled clinical trial

Baek,

Ha,

Park

et al. 2023

BMC Complement Med Ther

View full text Add to dashboard Cite

Background This trial aimed to evaluate the anti-obesity effects and safety of Neoagaro-oligosaccharides (NAOs) in humans in a 16 week, randomized, double-blind, placebo-controlled clinical trial. Methods One hundred overweight or obese subjects with a body mass index of 23 to 34.9 kg/m2 and a percent body fat of > 25% for males or > 30% for females were enrolled. NAOs or placebo products were administered at 3 g (twice a day, four capsules once) each for 16 weeks. Efficacy and safety biomarkers were measured before and after intervention. Results After 16 weeks of intervention, the group administered with NAOs had statistically significant decreases in visceral fat area and visceral-subcutaneous fat area ratio compared to the placebo group. The NAOs group suppressed the increase in weight and BMI compared to the placebo group, which was significant between groups. High-density lipoprotein- cholesterol was increased in the group administered with NAOs, which showed a significant trend compared to the placebo group. Clinical changes were not observed for any safety biomarkers. Conclusions These results suggest that NAOs have a beneficial effect on obesity. Thus, NAOs could be used as an anti-obesity supplement without side effects. Trial registration cris.nih.go.kr: (KCT0006640, 07/10/2021).

show abstract

Waist circumference, visceral abdominal fat thickness and three components of metabolic syndrome

Cited by 11 publications

References 16 publications

The Correlation between the Ratio of Visceral Fat Area to Subcutaneous Fat Area on Computed Tomography and Lipid Accumulation Product as Indexes of Cardiovascular Risk

The Correlation between the Ratio of Visceral Fat Area to Subcutaneous Fat Area on Computed Tomography and Lipid Accumulation Product as Indexes of Cardiovascular Risk

Association between triglyceride-glucose related indices with the all-cause and cause-specific mortality among the population with metabolic syndrome

Anti-obesity effect of Neoagaro-oligosaccharides with overweight and obese subjects: a 16-week, randomized, double-blind, placebo-controlled clinical trial

Contact Info

Product

Resources

About