Waist circumference for the screening of the metabolic syndrome in children

Moreno, LA; Pineda, I; Rodrı́guez, Gerardo; Fleta, J; Sarrı́a, Antonio; Bueno, Manuel

doi:10.1111/j.1651-2227.2002.tb02825.x

Cited by 249 publications

(111 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Simple waist circumference measurements appear to have a similar performance to that of BMI in screening for the metabolic syndrome (21). Moreover, a single measurement, not a ratio, reduces the chance of error.…”

Section: Discussionmentioning

confidence: 88%

Homeostatic model assessment (HOMA) index cut-off values to identify the metabolic syndrome in children

Tresaco

Bueno

Pineda

et al. 2005

J. Physiol. Biochem.

149

View full text Add to dashboard Cite

The aim of the study was to establish the best cut-off value for the homeostatic model assessment (HOMA) index in identifying children and adolescents with the metabolic syndrome. The study included 72 non-obese and 68 obese children aged 7 to 16 years. Obesity is defined using the criteria proposed by Cole et al., being included as metabolic syndrome variables waist circumference, systolic blood pressure, diastolic blood pressure and seric values of glucose, uric acid, fasting insulin, leptin, triglycerides and HDL-cholesterol. Children were considered as having the metabolic syndrome when four or more characteristics showed abnormal values. The HOMA index was calculated as the product of the fasting plasma insulin level (microU/mL) and the fasting plasma glucose level (mmol/L), divided by 22.5. HOMA index cut-offs from the 5th to the 95th percentile were used. A receiver operating characteristic (ROC) curve was generated using the different HOMA cut-offs for the screening of the metabolic syndrome. The areas under the ROC curve, 95% confidence intervals, and the point to the ROC curve closest to 1, were calculated. The area under the ROC curve was 0.863 (95% C.I.: 0.797, 0.930). The point closest to 1 corresponds to the 60th percentile of the HOMA index distribution in our sample. HOMA index value at the 60th percentile was 2.28. Cut-off values corresponding to a range of HOMA index from the 50 to the 75 percentile, showed similar distances to 1. HOMA index values for percentiles 50 to 75 ranged from 2.07 to 2.83. In conclusion, HOMA index could be a useful tool to detect children and adolescents with the metabolic syndrome. HOMA cut-off values need to be defined in the paediatric population; however, values near to 3 seem to be adequate.

show abstract

Section: Discussionmentioning

confidence: 88%

Homeostatic model assessment (HOMA) index cut-off values to identify the metabolic syndrome in children

Tresaco

Bueno

Pineda

et al. 2005

J. Physiol. Biochem.

149

View full text Add to dashboard Cite

show abstract

“…WC reflects abdominal fat and visceral tissue [25,26], which seems to be a good predictor of metabolic syndrome in children [27]. Multiple screening tools are available to identify the body fat distribution in children.…”

Section: Discussionmentioning

confidence: 99%

Body Mass Index or Waist Circumference: Which Is the Better Predictor for Hypertension and Dyslipidemia in Overweight/Obese Children and Adolescents? Association of Cardiovascular Risk Related to Body Mass Index or Waist Circumference

Gröber-Grätz

Widhalm²,

Zwaan³

et al. 2013

Horm Res Paediatr

View full text Add to dashboard Cite

Background: In order to assess the relationship between hypertension or dyslipidemia and obesity, the body mass index (BMI) is usually used. Unlike waist circumference (WC), BMI does not reflect body fat distribution. The aim of this study is to investigate whether BMI or WC is a better predictor of hypertension or dyslipidemia in overweight/obese children and adolescents. Methods: As of November 2012, the APV database contained data on 81,819 patients from 189 specialized pediatric obesity institutions in Germany, Austria and Switzerland. Logistic regression analysis was conducted using odds ratios (OR) with 95% CI. Results: The average age of the youths (n = 5.978) was 13.9 ± 1.8 years. Mean BMI-SDS was 2.0 ± 0.5, and mean WC-SDS was 2.2 ± 0.5. Both BMI-SDS and WC-SDS are significant predictors of hypertension and dyslipidemia: BMI-SDS is a better predictor (OR = 2.60) for hypertension than WC-SDS (OR = 1.85), while WC-SDS (OR = 1.90) was slightly superior to BMI-SDS (OR = 1.86) in predicting adverse lipid profiles. Compared to normal-weight patients, obese patients (BMI ≥97th percentile) exhibited increased systolic (+6.3 mm Hg) and diastolic blood pressure (+3.9 mm Hg). However, this difference was only +4.8 mm Hg (systolic) and +2.6 mm Hg (diastolic) if WC >97th percentile was used. Conclusion: BMI-SDS is more closely associated with hypertension, while WC-SDS is more closely associated with dyslipidemia. However, the additional measurement of WC has only a small benefit in obese youths.

show abstract

“…1 Whereas the best methods for estimating abdominal fat are imaging techniques, an anthropometric surrogate (waist circumference) is used for population studies. For children and adolescents, data on temporal changes in abdominal adiposity are scarce.…”

mentioning

confidence: 99%

Secular trends in waist circumference in Spanish adolescents, 1995 to 2000-02

Moreno

Sarrı́a²,

Fleta³

et al. 2005

Archives of Disease in Childhood

View full text Add to dashboard Cite

Two studies, in 1995 and 2000-02, were compared to assess changes in waist circumference in adolescents. Between the two time periods, waist circumference increased significantly in males at 13 years and in females at 14 years. Significant changes in waist circumference were observed during the study period; the rates of change were 0.53 and 0.86 cm/y in boys and 0.67 and 0.87 cm/y in girls. Future morbidity in adolescents may be affected due to accumulation of excess central fat.A bdominal adiposity is a component of the metabolic syndrome, already observed in children and adolescents. 1Whereas the best methods for estimating abdominal fat are imaging techniques, an anthropometric surrogate (waist circumference) is used for population studies. For children and adolescents, data on temporal changes in abdominal adiposity are scarce. In British youth, McCarthy and colleagues 2 have observed trends in waist circumference that greatly exceeded those in BMI, particularly in girls. To establish preventive measure to fight childhood obesity and its consequences there is a need to monitor total and abdominal adiposity in children and adolescents. The aim of this study was to assess recent changes in waist circumference in Spanish adolescents. METHODS AND RESULTSIn this study we consider data from two cross-sectional studies, both representative of Zaragoza (Spain). The first was conducted in 1995;3 for this analysis we have included 233 adolescents (aged 13-14 years; 128 boys and 105 girls). The second was conducted within the framework of the AVENA Study, from January 2000 to March 2002; for this analysis, we have included 162 adolescents (aged 13-14 years; 72 boys and 90 girls). The protocol of the AVENA Study was approved by the Review Committee for Research Involving Human Subjects of the Hospital Universitario Marqués de Valdecilla (Santander, Spain).Weight and height were measured and the body mass index (BMI) was calculated. Waist circumference was measured with an inelastic tape: the subject was in a standing position, and the tape was applied horizontally midway between the lowest rib margin and the iliac crest, at the end of gentle expiration; 4 technical error of measurement was 0.95 cm, and reliability 98.0%. 4 The technical error of measurement was obtained by carrying out a number of repeated measurements on the same subject, by the same observer; the coefficient of reliability reveals what proportion of the between-subject variance in a measured population is free from measurement error.For each survey we calculated means and standard deviations by sex and age. Comparisons were done by the Mann-Whitney U test. Multiple regression analysis was used to assess whether the effect of time in waist circumference changes was independent of the change in total adiposity assessed by the BMI; independent variables included in the regression model were BMI and the time when the waist measurements were taken. Table 1 shows changes in BMI and waist circumference in Zaragoza from 1995 to 2000-02. For waist circumferen...

show abstract

Waist circumference for the screening of the metabolic syndrome in children

Cited by 249 publications

References 24 publications

Homeostatic model assessment (HOMA) index cut-off values to identify the metabolic syndrome in children

Homeostatic model assessment (HOMA) index cut-off values to identify the metabolic syndrome in children

Body Mass Index or Waist Circumference: Which Is the Better Predictor for Hypertension and Dyslipidemia in Overweight/Obese Children and Adolescents? Association of Cardiovascular Risk Related to Body Mass Index or Waist Circumference

Secular trends in waist circumference in Spanish adolescents, 1995 to 2000-02

Contact Info

Product

Resources

About