W1853 Ten-Year Outcome of Laparoscopic and Conventional Nissen Fundoplication: Randomized Clinical Trial

Broeders, Joris A.; Jong, Hilda G. Rijnhart-de; Draaisma, Werner A.; Broeders, Ivo A. M. J.; Smout, A. J. P. M.; Gooszen, Hein G.

doi:10.1016/s0016-5085(09)63412-0

Cited by 35 publications

(48 citation statements)

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“…34,35 The 10-year results of 2 RCTs comparing LNF and CNF have demonstrated that laparoscopic fundoplication reduces the incidence of incisional hernias 36 and incisional hernia corrections. 37 In contrast, the current study reports only 1 incisional hernia correction in the first laparoscopic cohort and none in the open group and the second laparoscopic cohort at 5 years. Our group has previously demonstrated that the higher rate of incisional hernias after open surgery is not present at 5 years 18 and becomes clinically relevant between 5 and 10 years of follow-up.…”

Section: Commentcontrasting

confidence: 64%

Impact of Surgeon Experience on 5-Year Outcome of Laparoscopic Nissen Fundoplication

Broeders

Draaisma²,

Jong³

et al. 2011

Arch Surg

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To investigate the 5-year effect of surgeon experience with laparoscopic Nissen fundoplication (LNF). In 2000, a randomized controlled trial (RCT) was prematurely terminated because LNF for gastroesophageal reflux disease was associated with a higher risk to develop dysphagia than conventional Nissen fundoplication (CNF). Criticism focused on alleged bias caused by the relative lack of experience with the laparoscopic approach of the participating surgeons.Design: Multicenter RCT and prospective cohort study.Setting: University medical centers and tertiary teaching hospitals.Patients: In the RCT, 74 patients underwent CNF and 93 patients underwent LNF (LNFI). The complete setup of the cohort study (LNFII) (n = 121) mirrored the RCT, except that surgeon experience increased from more than 5 to more than 30 LNFs per surgeon.

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Section: Commentcontrasting

confidence: 64%

Impact of Surgeon Experience on 5-Year Outcome of Laparoscopic Nissen Fundoplication

Broeders

Draaisma²,

Jong³

et al. 2011

Arch Surg

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“…Total fundoplication according to Nissen provides excellent reflux control and is the most frequently performed operation for GERD. [1][2][3] However, laparoscopic…”

Section: Introductionmentioning

confidence: 99%

Laparoscopic Anterior 180-Degree Versus Nissen Fundoplication for Gastroesophageal Reflux Disease

et al. 2013

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Running headAnterior 180˚ versus Nissen fundoplication for GERD: a meta-analysis Word count 3161Archived at the Flinders Academic Commons: http://dspace.flinders.edu.au/dspace/ 2 Mini-AbstractSystematic review and meta-analysis demonstrating that laparoscopic anterior 180˚ fundoplication (180˚ LAF) reduces short and longer-term dysphagia and gas-related symptoms compared to laparoscopic Nissen fundoplication, with similar reflux control, dilatations and reoperation rate. These results lend level 1a support for the use of 180˚ LAF for the surgical treatment of GERD.Archived at the Flinders Academic Commons: http://dspace.flinders.edu.au/dspace/ 3 Structured abstractObjective: To compare short and longer-term outcome after laparoscopic anterior 180˚ fundoplication (180˚ LAF) versus laparoscopic Nissen fundoplication (LNF). Summary of background data:LNF is currently the most frequently performed surgical therapy for GORD. Alternatively, 180˚ LAF has been alleged to reduce troublesome dysphagia and gas-related symptoms, with similar reflux control. Methods Conclusions:At one and five years, dysphagia and gas-related symptoms are lower after 180˚ LAF compared with LNF, and esophageal acid exposure and esophagitis are similar, with no differences in heartburn scores, patient satisfaction, dilatations and reoperation rate.These results lend level 1a support for the use of 180˚ LAF for the surgical treatment of GERD.

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“…It achieves similar long-term reflux control, with less short and long-term problems, compared to open fundoplication. 1 Laparoscopic Nissen fundoplication is the most frequently performed antireflux operation and alters the anatomy of the gastroesophageal junction. The gastroesophageal junction serves three functions.…”

Section: Introductionmentioning

confidence: 99%

“…Nissen fundoplication restores the third function and provides excellent reflux control. [1][2][3] However, it delivers a supracompetent valve which can impair the first two functions. Three meta-analyses have demonstrated that Nissen fundoplication is followed by a significant incidence of troublesome postfundoplication side effects, including troublesome postoperative dysphagia and gas related problems.…”

Section: Introductionmentioning

confidence: 99%

Five-Year Outcome After Laparoscopic Anterior Partial Versus Nissen Fundoplication

et al. 2012

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Mini-AbstractAnalysis of original data of 5-year outcomes from 461 patients enrolled in 4 randomized trials demonstrates that laparoscopic anterior 180˚ partial fundoplication is an effective treatment for gastroesophageal reflux, but with less side effects compared with Nissen fundoplication, although reflux control following anterior 90˚ partial fundoplication appears less effective than after Nissen fundoplication.

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W1853 Ten-Year Outcome of Laparoscopic and Conventional Nissen Fundoplication: Randomized Clinical Trial

Cited by 35 publications

References 0 publications

Impact of Surgeon Experience on 5-Year Outcome of Laparoscopic Nissen Fundoplication

Impact of Surgeon Experience on 5-Year Outcome of Laparoscopic Nissen Fundoplication

Laparoscopic Anterior 180-Degree Versus Nissen Fundoplication for Gastroesophageal Reflux Disease

Five-Year Outcome After Laparoscopic Anterior Partial Versus Nissen Fundoplication

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