W1615: Incidence, Management and Outcomes of Small Bowel (SB) Neoplasms in a Cohort of 2000 Patients Undergoing Video Capsule Endoscopy (CE): A Single Center Experience

Fujii, Larissa L.; Sharma, Virender K.; Decker, G.A.; Yadav, Anitha; Gurudu, Suryakanth R.; Malagon, Isaac; Leighton, Jonathan A.

doi:10.1016/j.gie.2010.03.1023

Cited by 5 publications

(7 citation statements)

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“…Confirming data previously reported in surgical series [9,10] the majority of tumors identified by CE (from6 3% [31] to 86% [38]) are malignant neoplasms and the most frequent histological types area denocarcinomas, carcinoids (in about 20% of cases each [30,31,34]), and GISTs. Of note, this tumor accounted for more than one third of all collected cases in the large multi-center European study [39].…”

Section: ❚ Introductionsupporting

confidence: 88%

“…One study [32] reported a prevalence of small bowel tumors in patients undergoing CE higher than 30%; however in this paper the Authors described lesions as "tumour" without histological confirmation. Tw o recent studies, coming from the USA and Europe, one of them published only in abstract form [38,39], examined large populations of patients undergoing CE (respectively 2000 [38] and moret han 5000 cases [39]) in whom the definitive diagnosis was confirmed by means of tissue sampling (Table 2). They both reported a small-bowel tumor frequency of 2.4%, only slightly above that reported in previous surgical series.…”

Section: ❚ Capsule Endoscopy In the Diagnosis Of Small-bowel Tumorsmentioning

confidence: 99%

“…All the papers previously mentioned reported that in patients with small-bowel neoplasm identified by CE, surgery alone or surgery plus chemotherapy is the treatment of choice in about 68-90% of cases [30][31][32]38,39]. Nevertheless, recent studies [38] showed that the identification of the small bowel tumor with CE can also lead to less invasive procedures such as polypectomy,e ndoscopic mucosal resection or chemotherapy alone.…”

Section: ❚ Impact Of Capsule Endoscopy On Clinical Outcomesmentioning

confidence: 99%

“…Small-bowel tumors appear at CE as masses (Fig. 1) or polyps in about 70-80% of cases [31][32][33][34][35][36][37][38][39] and as ulcers ( Fig. 2) (sometimes actively bleeding) or stenoses in 20-30% of cases.…”

Section: ❚ Introductionmentioning

confidence: 99%

“…Unfortunately, it is not possible to determine pathology and tumor type based on the capsule endoscopic appearance of lesions. These tumors are located, based on the capsule transit time, in about 50% of cases in them id-or distal small bowel [31][32][33][34][35][36][37][38][39]. This could be ap artial explanation of the extensive (and mainly negative) diagnostic work-up performed in patients enrolled in all these studies.…”

Section: ❚ Introductionmentioning

confidence: 99%

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Current role of small-bowel capsule endoscopy in neoplastic diseases

Pennazio¹,

Franchis²,

Rondonotti³

2011

Cancérodig.

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Although small-bowel tumors areas mall proportion of gastrointestinal neoplasms recent studies suggest that the incidence of these diseases is increasing. In fact, using new diagnostic modalities,t heir frequency has been shown to be slightly superior than previously thought. Until recently,diagnosis and management of these tumors wered elayed by the difficult of access to the small bowel and the poor diagnostic capabilities of the available diagnostic techniques. An array of new methods has recently been developed, increasing the possibility of detecting these tumors at an earlier stage. In this particular subset of patients capsule endoscopy,d espite its possible limitations, may provide crucial information changing the subsequent patient management and possibly influencing the long-term clinical outcome.

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