Vulvo-cervico-vaginal manifestations and evaluation of Papanicolaou smears in pemphigus vulgaris and pemphigus foliaceus

Barbosa, Natasha D. Fairbanks; Aguiar, Lana Maria de; Maruta, Celina Wakisaka; Aoki, Valéria; Sotto, Mírian Nacagami; Labinas, Glaucia H.O.; Périgo, Alexandre M.; Santi, Cláudia Giuli

doi:10.1016/j.jaad.2011.10.004

Cited by 16 publications

(1 citation statement)

References 17 publications

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“…In our series, involvement of other mucous was more frequent in patients with severe mucocutaneous type of PV than in patients with moderate or mild PV ( p =0.01). The involvement of genital mucosa was reported as second in terms of frequency in certain previous cohorts [ 16 , 32 ]. In our study, laryngeal involvement was present in 3 patients (9.9%).…”

Section: Discussionmentioning

confidence: 99%

Pemphigus Vulgaris: A Clinical Study of 31 Cases (2004–2014) in Morocco

Titou

Chahnoun

Tarik

et al. 2020

Dermatology Research and Practice

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Background. Pemphigus vulgaris is a rare bullous autoimmune dermatosis whose evolution and prognosis are unpredictable. Aim. The objective was to analyze long-term outcomes in patients with pemphigus vulgaris by identifying the factors that are able to influence prognosis, in particular the phenotype of pemphigus vulgaris, age at onset, multiplicity of mucosal involvement, relapse and remission rates, and survival functions. Methods. A retrospective analysis of a cohort of 31 patients followed for pemphigus vulgaris during the period from January 2004 to January 2014. Inclusion criteria were a diagnosis of pemphigus vulgaris confirmed by histopathology and direct immunofluorescence (DIF) and a period of follow-up of at least five years from the diagnosis. The following information was collected by a single investigator. Results. In total, 67.7% of patients presented a mucocutaneous pemphigus vulgaris. Male-female sex ratio was 2.4. The median duration of patient’s follow-up was estimated at 7 (6–9) years. Multiple mucosal involvement in the oral cavity and at other mucosal sites was significantly associated with severe mucocutaneous pemphigus vulgaris (p=0.01). Multiple relapses were significantly associated with the disease severity (p=0.04). Conclusion. Poor prognosis factors were severe mucocutaneous type of pemphigus vulgaris and multiple mucosal involvement in the oral cavity and at other mucosal sites.

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Section: Discussionmentioning

confidence: 99%