Vulvar Squamous Cell Carcinoma Metastatic to Skin of the Forearm

Ceydeli, Adil; Rucinski, James; Klipfel, Adam

doi:10.1097/00042728-200306000-00024

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“…7 Leg edema was noted in 5 of 7 previous cases where the absence or presence of leg edema was reported. 3,8 There has been only one reported case of cutaneous metastases to an upper extremity. The mode of transmission in that case was still presumed to be via lymphatic spread, given the history of right inguinal lymphadenopathy followed by the development of a right forearm metastasis.…”

Section: Discussionmentioning

confidence: 99%

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Epidermotropic metastasis from vulvar squamous cell carcinoma: A rare cutaneous manifestation

Wang

O’Brien

Ross

et al. 2010

Journal of the American Academy of Dermatology

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Section: Discussionmentioning

confidence: 99%

“…This was also the only case of a cutaneous metastatic vulvar cancer diagnosis in which the patient lived beyond 1 year. 8 Epidermotropic metastases have been described in relatively few cases and are most often attributed to breast cancer. 15 It is exceedingly rare for epidermotropic metastases to evolve from internal organ carcinomas.…”

Section: Discussionmentioning

confidence: 99%

Epidermotropic metastasis from vulvar squamous cell carcinoma: A rare cutaneous manifestation

Wang

O’Brien

Ross

et al. 2010

Journal of the American Academy of Dermatology

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A Unique History of the First Cases with Simultaneous Bone and Skin Metastasis in Vulvar Squamous Cell Carcinoma

Nasiri

Mousavi

Hasani

et al. 2017

J Obstet Gynecol Cancer Res

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Introduction: The incidence of vulvar cancer is nearly 5% of all gynecologic malignancies and almost 95% of vulvar cancers are squamous cell carcinoma (SCC). Recurrence is possible in 4 ways: local, regional, pelvic, and distant. In a cohort of 391 patients with vulvar SCC, distant metastasis was reported 5% .The common sites of distant metastasis are pelvic nodes, lung, and liver. Both skin and bone metastasis are rare in vulvar SCC. Case Presentation: The current report presented a 58-year-old female with the diagnosis of vulvar SCC. She was the 11th cutaneous metastasis, 13th bone metastasis, and the 1st case with simultaneous bone and skin metastasis reported in the last 60 years. Conclusions: It is necessary to consider any lesion on the vulve, especially in menopause females, and it should be the low threshold for biopsy to avoid delay in detection. After completion of selective treatment, the exact follow-up should be considered to discover metastases.

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Vulvar Squamous Cell Carcinoma Metastatic to Skin of the Forearm

Cited by 2 publications

References 4 publications

Epidermotropic metastasis from vulvar squamous cell carcinoma: A rare cutaneous manifestation

Epidermotropic metastasis from vulvar squamous cell carcinoma: A rare cutaneous manifestation

A Unique History of the First Cases with Simultaneous Bone and Skin Metastasis in Vulvar Squamous Cell Carcinoma

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