Vulvar leiomyoma in association with gastrointestinal leiomyoma

Ngo, Quan; Haertsch, Peter

doi:10.1111/j.1479-828x.2011.01338.x

Cited by 5 publications

(13 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Grossly, the tumors were well-circumscribed and had a gray, white, tan, or yellow cut surface. 2 , 3 , 5 , 7 – 9 , 12 , 14 , 16 – 22 Vulvar leiomyomas, like other smooth muscle tumors of the vulva, exhibit three principal histological patterns: spindled, epithelioid, and myxoid. 23 These patterns can be mixed or pure.…”

Section: Results (Table 1)mentioning

confidence: 99%

“… 24 On physical examination, palpation usually reveals a non-tender mass with firm consistency and partial mobility. 12 , 14 , 19 Occasionally, palpation also reveals a peduncle in a superficial mass 7 or simply a swelling in a deeper mass. 24 Tenderness may also be present in those patients who experience pain.…”

Section: Results (Table 1)mentioning

confidence: 99%

“…As mentioned above, vulvar leiomyoma often presents as a painless mass that enlarges over time, and it is usually initially misdiagnosed as a Bartholin’s cyst or abscess. 5 , 8 , 11 , 12 , 19 , 24 , 35 The most common clinical findings 20 of a Bartholin’s cyst or abscess is a painful lump that is often associated with fever and inflammation. The presence of tenderness should be determined by physical examination.…”

Section: Results (Table 1)mentioning

confidence: 99%

“…Excision of vulvar leiomyomas is the only viable surgical option to ensure complete cure. 2 , 3 , 14 , 19 Usually, the most important consideration for women who undergo surgery is simply the inconvenience. 2 , 4 , 7 , 12 , 22 , 35…”

Section: Results (Table 1)mentioning

confidence: 99%

See 3 more Smart Citations

Review of the pathophysiology, diagnosis, and therapy of vulvar leiomyoma, a rare gynecological tumor

et al. 2017

View full text Add to dashboard Cite

The objective of this article is to discuss the pathophysiology, diagnosis, differential diagnosis, and therapy of vulvar leiomyoma. We performed a review of all English-language reports of vulvar leiomyoma published in PubMed from 1978 to 2015 using the following search terms: “vulval leiomyoma,” “vulvar leiomyoma,” “vulval smooth muscle tumor,” and “external genitalia smooth muscle tumor.” Vulvar leiomyomas, which are rare benign monoclonal tumors, most commonly occur in the fourth and fifth decades of life. The genetics of vulvar leiomyoma remain undefined. Three principal histological patterns have been identified: spindled, epithelioid, and myxoid. Imaging tests such as ultrasound, endoscopic ultrasound, and magnetic resonance imaging are used in diagnosis. Surgical excision is the only curative treatment for vulvar leiomyomas. Establishment of a full differential diagnosis list and correct final diagnosis before surgery are essential for optimal clinical management. Although recurrence of vulvar leiomyoma is extremely rare, long-term follow-up of all cases is advisable.

show abstract

Section: Results (Table 1)mentioning

confidence: 99%

Section: Results (Table 1)mentioning

confidence: 99%

Section: Results (Table 1)mentioning

confidence: 99%

Section: Results (Table 1)mentioning

confidence: 99%

See 2 more Smart Citations

Review of the pathophysiology, diagnosis, and therapy of vulvar leiomyoma, a rare gynecological tumor

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Spindled is the most common. The excision of perineal leiomyomas is the most useful surgical option to cure leiomyomas completely (4,11,16,17). Though the recurrence is uncommon, a short-time follow-up is still suggested.…”

Section: Discussionmentioning

confidence: 99%

Perineal leiomyoma in a postmenopausal woman: A case report

Sui

Sun

et al. 2016

Oncology Letters

View full text Add to dashboard Cite

Abstract. Leiomyomas in the female reproductive system are commonly located in the uterus and typically regress following the menopause. Vulval leiomyomas are rare, and to the best of our knowledge, perineal leiomyomas in postmenopausal women have not been previously reported in the literature. The present case describes a 60-year-old Chinese woman who experienced perineal tenderness and lumbosacral radiating pain. The patient, who went through the menopause 12 years previously, had presented with a painful perineal mass for 1 year, which was subsequently diagnosed as a postmenopausal perineal leiomyoma. The mass was locally resected, and histopathological examination of the lesion resulted in a diagnosis of benign epithelioid leiomyoma. Immunohistochemical staining identified that the leiomyoma was positive for estrogen receptor and negative for progesterone receptor expression. The patient was followed up for 1 year and did not experience any pain or recurrence. The symptoms of local and lumbosacral radiating pain are extremely rare and may be induced by peripheral nerve stimulation. The etiology of postmenopausal perineal leiomyoma may be associated with infection, dietary, stress and environmental factors, and the role of estrogen cannot be overemphasized in cases of postmenopausal leiomyoma.

show abstract