Vulvar leiomyoma: a case report

Abstract

Leiomyomas represent about 3.8% of all benign soft tissue tumors. Vulvar localization is very rare. We present a case of a vulvar leiomyoma and discuss diagnostic and therapeutic features of this disease. A 30-year-old female patient with no medical history, had a 5cm mass located in the left large lip causing a discomfort at the perineum especially in sitting and walking. She underwent a complete surgical excision of the mass. The pathological examination confirmed the diagnosis of a leiomyoma. There was no recurrence after 24-months' follow-up. The vulvar leiomyoma is a rare benign tumor. The diagnosis is made only postoperatively after resection of the mass. The treatment is essentially based on total excision of the mass with a good prognosis.

A rare case of benign vulvovaginal leiomyoma: Case report and literature review

“…The causes of vulvar leiomyoma are still unknown, but estrogens and progesterone are believed to play a role in tumor proliferation, given that fibroids rarely arise before menarche and frequently disappear after menopause [ 6 , 21 ]. It is also important to highlight that Tavassoli and Norris observed it is unlikely that the tumor will change in its growth or invasion during pregnancy [ 22 ].…”

Vulvar leiomyoma in an adolescent girl: a case report and review of the literature

“…Leiomyomas are well-circumscribed, benign soft tissue neoplasms of mesenchymal origin, with the uterus being the most frequent site [ 1 ]. Extrauterine leiomyomas are extremely rare, and can originate from vulva, vagina, ovaries, urinary bladder, urethra, round ligaments, uterosacral ligaments, inguinal canal, retroperitoneum, sinonasal cavities, and kidney [ 2 ].…”

A rare case of vulvar leiomyoma masquerading as Bartholin cyst

“…So far not more than 160 cases of vulvar leiomyoma have been recorded in the literature (4). The risk factors for its occurrence are not well articulated, and it has been postulated that estrogen and progesterone play a role in tumor proliferation (5). Before menarche occurrence of leiomyoma are rare and after menopause, they often undergo regression (6).…”