Vulvar intraepithelial neoplasia and vulvar squamous cell carcinoma: differential dermoscopic features in a case series, and a progression model

Vaccari, Sabina; ­Barisani, Alessia; Preti, Eleonora Petra; Dika, Emi; Fanti, Pier ­Alessandro; Patrizi, Annalisa; Tosti, Giulio

doi:10.1111/ced.13380

Cited by 9 publications

(6 citation statements)

References 6 publications

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“…[11] Dermoscopy of dVIN shows pink to red, structureless, background with red areas due to superficial erosions and vascular structures (consisting of curvy, short, serpentine, and dotted vessels). [12] Histopathology Indications for biopsy include:…”

Section: Dermoscopymentioning

confidence: 99%

Vulvar premalignancies – A dermatologist’s perspective

Kavitha

Deeksha²

2022

JSSTD

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Vulvar malignancies are rarely encountered in dermatology, yet it is imperative to develop a thorough clinical and diagnostic acumen, as early detection and appropriate treatment can improve quality of life or even prevent fatal outcome. The common premalignant vulvar lesions are vulvar intraepithelial neoplasia (VIN), vulvar Paget’s disease, and melanoma in situ. These are notable since they are associated with a high post-treatment recurrence rate. The incidence of VIN is increasing in younger women. Early diagnosis and tailoring the management on individual basis may help to reduce the long-term morbidity. This review describes etiology, clinical features, management, and prognosis of vulvar premalignancies.

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Section: Dermoscopymentioning

confidence: 99%

Vulvar premalignancies – A dermatologist’s perspective

Kavitha

Deeksha²

2022

JSSTD

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“…ŜƍƅƖżƈƋƄƈƉƟƙ žźƝ ƁƆƈŽƍ żƋƌźƇƈżƂƌƂ ƆſƀƟ ƈƋſ-ƊſžƄź ƍƊźƀſƇƇƙ, żƂƙżƂƌƂ ƋźƌſƅƟƌƇƟ ƌź ƆƇƈƀƂƇƇƟ ƈƋſƊſžƄƂ, ƙƄƟ Ƈſ żƂƁƇźƑźƘƌƖƋƙ ƇſƈƁŻƊƈƝƇƂƆ ƈƄƈƆ, ź ƌźƄƈƀ žƟƅƙƇƄƂ, žſ ƉƈƑƂƇźƘƌƖƋƙ ƟƇżźƁƟƠ [13,16,17].…”

Section: ŝƌƌƍɖunclassified

Efficacy assessment of the clinical dermoscopy and vulvoscopy examination in vulvar intraepithelial neoplasia

Dunaevskaya¹,

Tatarchuk²

2022

UJHW

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High grade squamous intraepithelial lesions of the vulva of the usual type are associated with infection caused by human papillomavirus, while differentiated intraepithelial neoplasia of the vulva develops most often on the background of vulvar lichen sclerosus et atrophicus in postmenopausal women. These types of intraepithelial neoplasia can be analyzed using dermoscopy and vulvoscopy methods. Purpose - to evaluate the effectiveness of clinical dermatoscopy and vulvoscopic examination in vulvar intraepithelial neoplasia. Materials and methods. This research paper presents the results of using dermoscopy and vulvoscopy examination methods, their comparison with the histological result and determining the most effective of these methods taking into account a higher probability of suspected precancerous lesions of the vulva. Results. The study involved 170 patients who were examined in the outpatient department of the National Cancer Institute in 2017-2021. 100 (58.82%) patients were diagnosed with the usual type vulvar intraepithelial neoplasia, 70 (41.17%) patients - of the differentiated type. Conclusions. The study results proved that dermoscopy was more exact to suspect precancer and a more accurate biopsy taking was fixed. The detection of НSIL was 98% in patients who underwent dermoscopy and those who had vulvoscopy - 75%, compared with histological findings. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of all participating institutions. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the authors.

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“…The diagnosis of case 2 was challenging because it was a combined lesion, displaying both dermoscopic features typical of VM 3,5 and of H-SIL. [5][6][7][8] The pathologic findings are responsible for the polymorphous dermoscopic features. Dermoscopy was useful to perform a biopsy promptly.…”

Section: Casementioning

confidence: 99%

Vulvar melanoma: How good are we in the follow‐up of high‐risk women?

Tosti

Barisani

Iacobone

et al. 2020

Dermatologic Therapy

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Vulvar melanoma (VM) represents 2% to 10% of all vulvar malignancies. 1,2 The diagnosis is often late. We previously showed that VM can be diagnosed at an early stage with the aid of digital dermoscopy. 3 Little is recognized about the use of dermoscopy in the follow-up of patients who received surgery for primary VM. We report two cases of tiny pigmented lesions promptly diagnosed during follow-up in patients who received surgery for a prior VM.

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Vulvar intraepithelial neoplasia and vulvar squamous cell carcinoma: differential dermoscopic features in a case series, and a progression model

Cited by 9 publications

References 6 publications

Vulvar premalignancies – A dermatologist’s perspective

Vulvar premalignancies – A dermatologist’s perspective

Efficacy assessment of the clinical dermoscopy and vulvoscopy examination in vulvar intraepithelial neoplasia

Vulvar melanoma: How good are we in the follow‐up of high‐risk women?

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