Vulvar hidradenitis suppurativa: Clinical cross‐sectional study of 25 patients

López-Llunell, Cristina; Romaní, Jorge; Garbayo-Salmons, Patricia; Agut-Busquet, Eugènia

doi:10.1111/1346-8138.15728

Cited by 7 publications

(10 citation statements)

References 24 publications

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“…López-Llunell et al studied 25 patients with VHS and found that patients had late onset of disease. The average BMI of VHS was normal (HS with VHS: 23.2 kg/m 2 vs. HS without: VHS 28.6 kg/m 2 ) [ 73 ]. A nationwide cohort analysis in Denmark investigated medication of HS patients [ 74 ].…”

Section: Resultsmentioning

confidence: 99%

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The Role of Hormones in Hidradenitis Suppurativa: A Systematic Review

Rached

Gambichler

Dietrich

et al. 2022

IJMS

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Hidradenitis suppurativa (HS) is a chronic inflammatory disease manifesting in inverse body regions. In a systematic review, the role of hormones in HS will be presented to better understand the pathomechanisms of HS. The review is based on the PRISMA criteria. Systematic research was carried out using keywords. Subsequently, the data were analyzed based on the clinical response and other relevant information. The main focus of our systematic review was on HS manifestation, exacerbation, sex hormones, antiandrogen therapy, thyroid function, polycystic ovary syndrome, insulin resistance, and adipokines. In HS, there appears to be a dysregulated adipokine release that is shifted towards pro-inflammatory adipokines. Insulin resistance is significantly more common in HS than in healthy patients regardless of BMI, age, and gender. Insulin resistance in HS patients leads to further cardiovascular disease. The mechanism of insulin resistance and role of adipokines should be investigated in future studies to better provide the pathomechanisms of HS. The role of androgens seems to be important in a certain subgroup of female patients. Anti-androgenic therapy can be useful and helpful in some patients. However, further studies are needed to better understand the hormonal relationship in HS.

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Section: Resultsmentioning

confidence: 99%

“…However, the current data do not allow any clear conclusions to be drawn about thyroid function in HS. HS with vulva involvement was significantly associated with thyroid disease [ 73 ]. The reasons for this association are unknown.…”

Section: Discussionmentioning

confidence: 99%

The Role of Hormones in Hidradenitis Suppurativa: A Systematic Review

Rached

Gambichler

Dietrich

et al. 2022

IJMS

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“…5,6 Vulvar hidradenitis suppurativa is a highly rare diagnosis with limited reports on literature. 7 Here, we report a confirmed case of hidradenitis suppurativa limited to vulva which was initially diagnosed and managed as cutaneous endometriosis.…”

Section: Introductionmentioning

confidence: 90%

“…5,6 Vulvar hidradenitis suppurativa is a highly rare diagnosis with limited reports on literature. 7…”

Section: Introductionmentioning

confidence: 99%

Painful catamenial vulvar lesions misleading gynecologist

Yıldız

Bilir

Dikmen

et al. 2022

Journal of Endometriosis and Pelvic Pain Disorders

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Endometriosis usually presents as cyclical pain in the pelvis but may also present as painful cutaneous lesions. Many diseases may mimic hidradenitis suppurativa (HS) since HS, a chronic inflammatory painful skin disease, is a clinical diagnosis. A 32-year-old woman presented with painful lumps on her vulva and groin accompanied with bloody discharge during menstruation. She was followed up with preliminary diagnosis of endometriosis. Previous excision without definitive diagnosis resulted in temporary relief. She was prescribed oral contraceptive pills that alleviated her symptoms but quitted due to headache. Surgical excision was performed for definitive diagnosis and therapeutic relief. Pathology report revealed HS. She was prescribed oral doxycycline. She responded well to the therapy and has symptom-free for the last 2 years. She delivered one healthy girl via cesarian section 2 years after the treatment. Endometriosis and HS should be included in the differential diagnosis when women present with menstrual painful lesions around external genitalia for diagnosis and treatment.

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“…The global prevalence of HS has been reported in the 0.00033–4.1% range [ 5 , 6 ]. The exact etiology and pathogenesis of HS remains unclear [ 7 , 8 ]. The cause of follicular plugging is still under debate, although immune dysregulation, genetic factors, hormonal fluctuation, and environmental risk factors are thought to play a role [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Co-Graft of Acellular Dermal Matrix and Split Thickness Skin Graft—A New Reconstructive Surgical Method in the Treatment of Hidradenitis Suppurativa

et al. 2022

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Hidradenitis suppurativa is a chronic disease that significantly reduces patients’ quality of life. Patients are chronically treated with systemic therapies, which are often ineffective. Surgical treatment for severe cases of hidradenitis suppurativa is one option for affected patients. Surgical treatment has its limitations, and wound closure may be particularly problematic. This requires the use of reconstructive techniques. The methods of choice for wound closure are split-thickness skin grafts or local flaps reconstructions. However, each method has its limitations. This is a presentation of a new reconstructive surgical method in hidradenitis suppurativa surgery: the use of a co-graft of Acellular dermal matrix and split thickness skin graft as a novel method in wound closure after wide excisions, based on two cases. The results of this method are very promising: we achieved very fast wound closure with good aesthetic results regarding scar formation. In this paper, we used several examinations: laser speckle analysis, cutometer tests, and health-related quality of life (QoL) questionnaire to check the clinical impact of this method. Our initial results are very encouraging. ADM with STSG as a co-graft could be widely used in reconstructive surgery. This is a preliminary study, which should be continued in further, extended research.

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Vulvar hidradenitis suppurativa: Clinical cross‐sectional study of 25 patients

Cited by 7 publications

References 24 publications

The Role of Hormones in Hidradenitis Suppurativa: A Systematic Review

The Role of Hormones in Hidradenitis Suppurativa: A Systematic Review

Painful catamenial vulvar lesions misleading gynecologist

Co-Graft of Acellular Dermal Matrix and Split Thickness Skin Graft—A New Reconstructive Surgical Method in the Treatment of Hidradenitis Suppurativa

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