Vulva Fibroadenoma Associated with Lactating Adenoma in a 26-Year-Old Nigerian Female

Abstract

Background. Vulva lactating adenoma is rare and may be misdiagnosed as adenocarcinoma in frozen section and aspiration cytology if breast tissue is not anticipated. Objective. To raise the awareness of lactating vulva ectopic breast lesion among clinicians and pathologists. Case Report. We present a case of vulva fibroadenoma associated with lactating adenoma in a 26-year-old Nigerian female. Conclusion. The rarity of vulva ectopic breast tissue can present a diagnostic challenge for both the clinician and the anatomical pathologist. Once excisional biopsy is done and the lesion confirmed histologically, the anxious patient can be reassured.

Vulvar Fibroadenoma: Case report and review of literature

“…The ectopic breast tissue or mammary like anogenital glands tissue express hormone receptors which are detected by immunohistochemistry [4].…”

“…The differential diagnosis are epidermal cyst, follicular cyst, Bartholin's gland duct cyst, lipoma, pseudoangimatous stromal hyperplasia, fibrocystic disease and sclerosingadenosis. Extramammary Paget's disease, ductal/lobular/mucinous adenocarcinoma are malignant differentials [2,4]. Histopathological features are similar to breast fibroadenoma showing a well-defined capsule, epithelial and stromal proliferation with compressed glands and fibromyxoid stroma surrounding it.…”

Ectopic Breast Tissue in the Vagina Detected at the Median Episiotomy Site

“…These glands are called mammary-like anogenital glands which are present in the anogenital region and are thought to be adnexal glands similar to mammary glands. Van der Putte's theory also states that the formation of these lesions does not require the existence of normal breast tissues [4,8,9]. In 2006, Atwal published a case of previously documented supernumerary mammary tissue-originating vulvar fibroadenoma, describing a lesion that histopathologically mimicked a fibroadenoma with positive estrogenic receptors on immunohistochemistry and with healthy mammary tissues surrounding the lesion [5].…”

Fine‐needle aspiration findings of fibroadenoma with pseudolactational changes in the vulva: A case report

“…1,2 Lactating adenoma and fibroadenoma with lactational changes are even more rare in the vulvar region. [3][4][5] Lactational changes uncommonly occur in breast fibroadenomas of nulliparous women and are known as pseudolactational changes. 6 So far, fibroadenoma with pseudolactational changes has not been reported in the vulva of nulliparous women.…”