VP62.07: Role of widespread ultrasound in the diagnosis of ovarian and tubal endometriosis

Abstract

Virtual poster abstracts and 3D transvaginal ultrasound (TVUS) measurements in women with abnormal uteri due to adenomyosis, leiomyomas or uterine anomalies. Methods: Design: Prospective observational cohort study. Population: 11 women with adenomyosis and 9 women with normal uteri. TVUS measurements: UC characterisation and analysis was implemented by a dedicated speckle-tracking algorithm with 2D/3D TVUS; with frequency, direction, amplitude and velocity-related features extracted from the derived signals. Measurements were carried out at different points of the menstrual cycle and in relation to hormonal therapy and IVF treatment. Results: Significantly higher contraction frequency was found in the healthy group during the peri-ovulatory phase (p < 0.05), but not during menstruation, compared to the adenomyosis patients. Contraction amplitude was significantly higher in the adenomyosis group, suggesting stronger uterine contractility (p < 0.05). No significant differences in terms of direction or velocity were observed. A further 60 women with abnormal uteri wil be included in this study. Conclusions: Study outcomes so far are promising, UC can be quantitatively described using a 2D/3D TVUS machine learning model. Results in specific populations show a clinically relevant application of this tool and confirm differences in uterine movement in abnormal versus healthy uteri. This adds to the aetiological understanding of clinical symptoms of these conditions (i.e. dysmenorrhoea, infertility). Further research in women with benign uterine disorders will lead to a better understanding of abnormal uterine contractility in this population.