Abstract:Objectives: To ascertain the performance of non-invasive prenatal screening (NIPS) as a frontline screening option in a population with high body mass index (BMI). Methods: 1,000 women attending a public hospital in Australia were offered NIPS free of charge as part of a study examining the uptake of NIPS in a low socioeconomic population in Australia. Samples were taken at 11-12 weeks of gestation and analysed using Illumina TruSeq v1.2 methodology and interpreted using the SaFER algorithms. Results: The aver… Show more
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