Vorzeitige Operation bei akuter hämorrhagisch-nekrotisierender Pankreatitis

Kümmerle, F; Neher, M; Schönborn, H.; Mangold, G

doi:10.1055/s-0028-1106529

Cited by 50 publications

(13 citation statements)

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“…In Germany, the Mainz group first advised early operation, i.e. necrosectomy soon after admission[21], and later recommended delayed surgery in order to be able to at least approximately demarcate the necroses[22]. In the middle of the 1980s, Germany and many other countries followed the indications for surgical management und surgical goals formulated by Beger and his group[23].…”

Section: Acute Pancreatitis In 20th Centurymentioning

confidence: 99%

Clinical pancreatology I: Pancreatic medical history

Andrén‐Sandberg¹

2010

NAJMS

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The present article and subsequent reviews will not be to report all what has been published, but rather to give an introduction samples that hopefully make the reader eager to read the whole article or articles with “a taste of clinical pancreatology in 2010”. The main sources of literatures were PubMed, and the additional Journals such as Pancreas, Pancreatology and Journal of the Pancreas were also scrutinized. Only some full articles in almost all languages were included in the review, other articles, however, that were too superficial or too poor in other ways, were omitted, and the publications of non-human study were excluded.

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Section: Acute Pancreatitis In 20th Centurymentioning

confidence: 99%

Clinical pancreatology I: Pancreatic medical history

Andrén‐Sandberg¹

2010

NAJMS

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“…30 min after the induction of experimental, acute hemorrhagic-necrotizing pancreatitis a significant increase of the activity in the serum of dogs is already evident. The observation can be of clinical significance as the choice of time for an operation is very important in the operative therapy of pan creatitis [8].…”

Section: Discussionmentioning

confidence: 99%

Serum DNase Activity after Experimental, Acute Hemorrhagic-Necrotizing Pancreatitis in Dogs: Detection of a Serum DNase Isoenzyme

Reitz¹,

Neher²,

Zöllner³

et al. 1981

Eur Surg Res

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The activity of a neutral serum DNase has been determined in dogs before and after experimental, acute hemorrhagic-necrotizing pancreatitis. Dog serum DNase corresponds in its conditions of activity and in its isoelectric point with the DNase I. Electrophoretically three DNase isoenzymes can be distinguished. 30 min after induction, an increase of DNase activity was observed. This activity increase is related to only one of the three DNase isoenzymes. After induction a DNase with an isoelectric point of 5.6 occurs. This enzyme is not found in healthy animals.

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“…Allerdings waren die Erghebnisse wenig ermutigend. So berichteten Ku È mmerle et al [6], daû in ihrem Patientenkollektiv von den 20 konservativ behandelten Patienten mit einer schweren, nekrotisierenden Pankreatitis niemand u È berlebte. Ebenso wie andere Autoren [7] beschlossen sie, zuku È nftig fru È hzeitiger zu operieren.…”

Section: Diskussionunclassified

Das Laparostoma in der chirurgischen Behandlung der hämorrhagisch-nekrotisierenden Pankreatits

Smektala¹

1999

Visc Med

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Treatment results of necrotising pancreatitis between 1982 and 1992 are reported. During the study period the management of necrotising pancreatitis was supplied by the laparostoma therapy. Within a standardised range of indications 118 patients with stage II and III of the disease were operated. The operative technique included distal pancreatectomy, necrectomy and debridement of the head of the pancreas. Among 72 patients (61.0%) a laparostoma treatment was applied, in 46 patients (39%) the abdominal cavity was closed post-operatively. A subsequent peritoneal lavage by stages was conducted within the laparostoma therapy group, in the other group the relaparotomy ensued from the clinical course. Although the degree of disease severity was more serious in the laparostoma group, the lethality rate could be reduced during the study period down to 21.4%. The lowest lethality rate was achieved by an operation after the 15th day of treatment.

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Vorzeitige Operation bei akuter hämorrhagisch-nekrotisierender Pankreatitis

Cited by 50 publications

References 1 publication

Clinical pancreatology I: Pancreatic medical history

Clinical pancreatology I: Pancreatic medical history

Serum DNase Activity after Experimental, Acute Hemorrhagic-Necrotizing Pancreatitis in Dogs: Detection of a Serum DNase Isoenzyme

Das Laparostoma in der chirurgischen Behandlung der hämorrhagisch-nekrotisierenden Pankreatits

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