Volvulus of the sigmoid colon

Raveenthiran, V; Madiba, T. E.; Atamanalp, Sabri Selçuk; De, Utpal

doi:10.1111/j.1463-1318.2010.02262.x

Cited by 177 publications

(381 citation statements)

References 113 publications

(233 reference statements)

Supporting

Mentioning

316

Contrasting

Unclassified

Order By: Relevance

“…In individuals with Hirschsprung' s disease, the functional obstruction of the aganglionic segment gives rise to massive dilatation and hypertrophy of the proximal ganglionic sigmoid colon, predisposing individuals to SV (8,13). Similar to Hirschsprung' s disease, acquired megacolon (in which, in contrast to Hirschsprung' s disease, ganglion cells are present in the bowel wall, but the loss of coordinating contractions ensues due to damage to the ganglion cells) is also accepted as a predisposing factor for the development of SV (3,12,(16)(17)(18)(19). Ryan (16) reported 6 SV cases with acquired megacolon, and Harbrecht and Fry (17) showed a similar relationship in 3 cases.…”

Section: Discussionmentioning

confidence: 99%

“…Hirschsprung' s disease (congenital aganglionic megacolon, the pathophysiology of which is described as the absence of ganglion cells in a bowel segment) is defined as a predisposing factor for the development of SV, and SV is observed more frequently in patients with this disease (3,(12)(13)(14)(15) (14) and Erdener et al (15) reported adult SV cases secondary to Hirschsprung' s disease. In individuals with Hirschsprung' s disease, the functional obstruction of the aganglionic segment gives rise to massive dilatation and hypertrophy of the proximal ganglionic sigmoid colon, predisposing individuals to SV (8,13).…”

Section: Discussionmentioning

confidence: 99%

“…Sigmoid volvulus (SV), known as far back as ancient Egypt, recognized by Hippocrates (1,2) and first described by von Rokitansky in 1836 (3), is a rarely observed type of large bowel obstruction in which the sigmoid colon wraps around itself and its own mesentery (4)(5)(6). Some predisposing factors for the development and recurrence of SV have been suggested and documented, including the presence of a redundant sigmoid colon with a high and narrow mesentery, advanced age, male sex, pregnancy, high altitudes, a highfiber vegetable diet, habitual constipation, and diseases such as adhesions, omphalomesenteric abnormalities, malrotations, intussusceptions, appendicitis, carcinomas, and particularly congenital or acquired megacolon (1)(2)(3)(4)(5)(6)(7).…”

Section: Introductionmentioning

confidence: 99%

“…Some predisposing factors for the development and recurrence of SV have been suggested and documented, including the presence of a redundant sigmoid colon with a high and narrow mesentery, advanced age, male sex, pregnancy, high altitudes, a highfiber vegetable diet, habitual constipation, and diseases such as adhesions, omphalomesenteric abnormalities, malrotations, intussusceptions, appendicitis, carcinomas, and particularly congenital or acquired megacolon (1)(2)(3)(4)(5)(6)(7). However, the role of the numerical density of the ganglion cells in the neural plexus has not been well investigated (8).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Stereological evaluation of ganglion cells in the sigmoid colon in primary and recurrent sigmoid volvulus

Atamanalp¹,

Gündoğdu²,

Ünal³

et al. 2013

Turk J Med Sci

View full text Add to dashboard Cite

New series of 2,5-disubstituted thiophenes were synthesized. Thiosemicarbazones 1a-b were reacted with various reagents, such as diethyl-2-bromomalonate, ethyl-2-chloroacetoacetate, thioglycolic acid, 4substituted phenacyl bromides, and acetic anhydride, to afford heterocyclic substituted thiophene derivatives 2a-b, 3a-b, 4a-b, 5a-b, 6a-b, and 7a-b, respectively. Moreover, cyclization of the key intermediate 1b with chloroacetic acid yielded thiazolidine 9, which on reaction with appropriate aromatic aldehydes afforded the corresponding arylidene derivatives 10a-f. Finally, reaction of N \ -arylidene cyanoacetohydrazide 11 with sulfur and phenylisothiocyanate yielded thiazoline derivative 12, which on treatment with triethylorthoformate and acetic anhydride afforded thiazolo[4,5-d ]pyrimidinone derivative 13. Some of the newly synthesized compounds showed promising antiinflammatory activity.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Stereological evaluation of ganglion cells in the sigmoid colon in primary and recurrent sigmoid volvulus

Atamanalp¹,

Gündoğdu²,

Ünal³

et al. 2013

Turk J Med Sci

View full text Add to dashboard Cite

show abstract

“…Although SV is an uncommon disease, its incidence is relatively high in Turkey, particularly in East Anatolia (2,3), where our hospital is located. The disease generally presents as large bowel obstruction and correct preoperative diagnosis is difficult (3).…”

mentioning

confidence: 99%

The role of CT and MRI in the diagnosis of sigmoid volvulus

Atamanalp¹,

Kantarcı²,

ÖZOĞLU³

et al. 2014

Turk J Med Sci

View full text Add to dashboard Cite

Sigmoid volvulus (SV) is the wrapping of the sigmoid colon around its own base (1). Although SV is an uncommon disease, its incidence is relatively high in Turkey, particularly in East Anatolia (2,3), where our hospital is located. The disease generally presents as large bowel obstruction and correct preoperative diagnosis is difficult (3).To examine the diagnostic role of computed tomography (CT) and magnetic resonance imaging (MRI) in SV, we reviewed the records of 960 patients with SV who were treated over a 47-year period between June 1966 and June 2013. Abdominal X-rays were obtained for all patients, while CT or MRI results were obtained for some stable patients of recent years. Both diagnostic and therapeutic sigmoidoscopy was performed in stable SV patients, while surgery was used in the patients with acute abdominal findings, melenic stools, and unsuccessful nonoperative detorsion. To determine the correct diagnosis rates, the diagnosis was corroborated by endoscopy or surgery.The correct diagnosis rate was 71.4% (685/960) based on the clinical findings, including abdominal pain, distention, and obstipation. Of the X-ray films, 67.4% (545/809) presented SV findings, including a sigmoid dilatation with intestinal airfluid levels. The correct diagnosis rate was 81.8% (785/960) when clinical findings were evaluated together with X-ray findings. Based on clinical and radiological considerations, SV was misdiagnosed as an obstructive emergency in 161 patients (16.8%) and as a nonobstructive emergency in 14 patients (1.5%). Sigmoidoscopy demonstrated 100.0% (144/144) correct diagnosis rate in patients in whom diagnostic endoscopy was applied by showing torsioned lumen and impossibility of the insertion of the instrument proximally into the torsioned site. Otherwise, 96.6% (57/59) and 97.4% of cases (37/38), respectively, were correctly diagnosed based upon CT and MRI findings by showing evidence of SV, including mesenteric whirl pattern with sigmoid dilatation and intestinal air-fluid levels. The major cause of misdiagnosis was the absence of the whirl sign, which resulted in improper diagnosis of nonspecific intestinal obstruction.The CT whirl sign, which was first determined by Fischer in 1981, is defined as twisted bowel loops encircling mesenteric vessels. It is an uncommon sign on CT and it is easy to overlook (4). Although Levsky et al. (5) reported the whirl sign in 12 of 21 patients with SV (57%) and they found the presence of sigmoid dilatation (86%) to be more sensitive, according to the report of Macari et al. (6), all 16 patients with SV had a CT whirl sign, which is in agreement with our results. In our opinion, the presence of the mesenteric whirl sign in addition to sigmoid dilatation and intestinal air-fluid levels on abdominal CT or MRI is highly diagnostic of SV. In addition to the preferable use of MRI in pregnant patients (7), the use of CT or MRI may improve preoperative diagnostic confidence in SV.

show abstract