Voluntary perioperative colorectal cancer registry from Kerala—An initial overview

Krishnan, Prasad; Kurumboor, Prakash; Varma, Deepak; Mallick, Shweta; Vayoth, Sudheer Othiyil; Gopalakrishnan, Unnikrishnan; Ramesh, H.; Subramaniaiyer, M.; Aikot, Sylesh; Nambiar, Rajesh; Sahadevan, Sajeesh; Rajan, Ramesh; Natesh, Bonny; Sadasivan, Sindhu Radha; Bhaskaran, Venugopal; Usman, Shabeerali Thudikkodan; Leela, Arunkumar Madhavan; Sadashiva, Sathchith; Kamalesh, N. P.; Abraham, Bejoy; Swaminathan, Peethambaran Muttikulangara; Philip, Sujith; Subash, Raveendran; Sreekumar, Vipin I

doi:10.1007/s12664-019-00998-9

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…Colorectal cancer (CRC) ranks among the six most common malignancies in India; yet, outcomes data outside of selected centers are lacking [5]. Krishnan and colleagues report the first outcomes data from 1018 CRC cases from 15/25 participating centers of the Association of Surgical Gastroenterologists of Kerala CRC registry between 2016 and 2018 [6]. The majority of CRC cases were rectal (39.88%) and rectosigmoid (20.33%), with minimally invasive surgery (MIS) performed in 73% cases and 56.74% of colonic malignancies.…”

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Editorial commentary on the Indian Journal of Gastroenterology May-June 2020

Limdi

2020

Indian J Gastroenterol

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The emergence of the Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-COV 2) from Wuhan, China in December 2019 and the resulting Corona Virus Disease (COVID-19) has gripped the world in a global pandemic from its unprecedented spread, changing our perceptions and paradigms around disease and the world, as we have known it. As of 11 July 2020, there have been 12,322,395 confirmed cases of COVID-19, including 556,335 deaths, reported to WHO [1] with 22,123 deaths in India [2]. Even as the world remains under the influence of this cataclysmic crisis, the medical and scientific communities have continued to work tirelessly and collaboratively to find answers for this hitherto unknown disease. Although a predominantly respiratory disease with multi-systemic ramifications, gastrointestinal (GI) symptoms such as diarrhea, vomiting, abdominal pain and hepatic abnormalities have been reported in up to 20% of patients with COVID-19, including those with minimal symptoms [3, 4]. The potential for SARS-COV2 to affect the GI tract and implications to patients with underlying GI and liver disease are of particular relevance to gastroenterologists. With this in mind, this issue focusses on COVID-19 with a series of research articles and clinical reviews on COVID-19 and GI disease, constituting essential and timely reading for the practising gastroenterologist. We hope you find these useful. And we wish you and your patients well…

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confidence: 99%

Editorial commentary on the Indian Journal of Gastroenterology May-June 2020

Limdi

2020

Indian J Gastroenterol

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Bridging Real-World Data Gaps: Connecting Dots Across 10 Asian Countries

Julian,

Shau,

Chou

et al. 2024

JMIR Med Inform

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The economic trend and the health care landscape are rapidly evolving across Asia. Effective real-world data (RWD) for regulatory and clinical decision-making is a crucial milestone associated with this evolution. This necessitates a critical evaluation of RWD generation within distinct nations for the use of various RWD warehouses in the generation of real-world evidence (RWE). In this article, we outline the RWD generation trends for 2 contrasting nation archetypes: “Solo Scholars”—nations with relatively self-sufficient RWD research systems—and “Global Collaborators”—countries largely reliant on international infrastructures for RWD generation. The key trends and patterns in RWD generation, country-specific insights into the predominant databases used in each country to produce RWE, and insights into the broader landscape of RWD database use across these countries are discussed. Conclusively, the data point out the heterogeneous nature of RWD generation practices across 10 different Asian nations and advocate for strategic enhancements in data harmonization. The evidence highlights the imperative for improved database integration and the establishment of standardized protocols and infrastructure for leveraging electronic medical records (EMR) in streamlining RWD acquisition. The clinical data analysis and reporting system of Hong Kong is an excellent example of a successful EMR system that showcases the capacity of integrated robust EMR platforms to consolidate and produce diverse RWE. This, in turn, can potentially reduce the necessity for reliance on numerous condition-specific local and global registries or limited and largely unavailable medical insurance or claims databases in most Asian nations. Linking health technology assessment processes with open data initiatives such as the Observational Medical Outcomes Partnership Common Data Model and the Observational Health Data Sciences and Informatics could enable the leveraging of global data resources to inform local decision-making. Advancing such initiatives is crucial for reinforcing health care frameworks in resource-limited settings and advancing toward cohesive, evidence-driven health care policy and improved patient outcomes in the region.

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Bridging Real-World Data Gaps: Connecting Dots Across 10 Asian Countries (Preprint)

Julian,

Shau,

Chou

et al. 2024

Preprint

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UNSTRUCTURED The economic trend and the healthcare landscape are rapidly evolving across Asia. Effective Real-World Data (RWD) for regulatory and clinical decision-making is a crucial milestone associated with this evolution. This necessitates a critical evaluation of Real-World Data (RWD) generation within distinct nations for utilization of various RWD warehouses in the generation of Real-World Evidence (RWE). In this article, we outline the RWD generation trends for two contrasting nation archetypes, ‘Solo Scholars’—nations with relatively self-sufficient RWD research systems—and ‘Global Collaborators’—countries largely reliant on international infrastructures for RWD generation. The key trends and patterns in RWD generation, country-specific insights into the predominant databases used in each country to produce RWE, and insights into the broader landscape of RWD database utilization across these countries are discussed. Conclusively, the data points out the heterogeneous nature of RWD generation practices across 10 different Asian nations and advocates for strategic enhancements in data harmonization. The evidence highlights the imperative for improved database integration and the establishment of standardized protocols and infrastructure for leveraging Electronic Medical Records (EMR) in streamlining RWD acquisition. The Clinical Data Analysis and Reporting System (CDARS) of Hong Kong is an excellent example of a successful EMR system that showcases the capacity of integrated robust EMR platforms to consolidate and produce diverse RWE. This, in turn, can potentially reduce the necessity for reliance on numerous condition-specific local and global registries or limited and largely unavailable medical insurance or claims databases in most Asian nations. Linking Health Technology Assessment (HTA) processes with open data initiatives like the Observational Medical Outcomes Partnership Common Data Model and the Observational Health Data Sciences and Informatics could enable the leveraging of global data resources to inform local decision-making. Advancing such initiatives is crucial for reinforcing healthcare frameworks in resource-limited settings and advancing towards cohesive, evidence-driven healthcare policy and improved patient outcomes in the region. International Registered Report Identifier (IRRID): RR2-10.2196/43741

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Voluntary perioperative colorectal cancer registry from Kerala—An initial overview

Cited by 3 publications

References 9 publications

Editorial commentary on the Indian Journal of Gastroenterology May-June 2020

Editorial commentary on the Indian Journal of Gastroenterology May-June 2020

Bridging Real-World Data Gaps: Connecting Dots Across 10 Asian Countries

Bridging Real-World Data Gaps: Connecting Dots Across 10 Asian Countries (Preprint)

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