“…TBI regulates brain miRNA expression acutely [14][15][16][17], and some miRNAs remain regulated chronically-months to years after TBI [18,19]. Dysregulated miRNA levels are reported in the cortex [9,14,[20][21][22], hippocampus [15,16,18,19,[23][24][25][26][27], and plasma [28][29][30]. Only a few studies, however, have addressed miRNA expression in patients with TBI [13,19,23,28], highlighting the gap between preclinical and clinical studies.…”