Voluminous Myoepithelioma of the Minor Salivary Glands Involving the Base of the Tongue

Policarpo, M; Longoni, Valentina; Garofalo, Pietro; Spina, Paolo; Pia, Francesco

doi:10.1155/2016/3785979

Cited by 2 publications

(1 citation statement)

References 10 publications

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“…In all cases reported the surgical treatment was performed and the recurrence has been associated with incomplete resection of tumor, which proves the aggressive biological behavior of this tumor [16, 17]. Histologically this tumor is well circumscribed, so complete excision is possible [18].…”

Section: Discussionmentioning

confidence: 99%

Myoepithelioma of the Nasal Septum: A Rare Case of Extrasalivary Gland Involvement

Cunha

Camurugy

Ribeiro

et al. 2017

Case Reports in Otolaryngology

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Introduction. The myoepithelioma is a rare benign tumor, most frequently found in the salivary glands. The extrasalivary gland involvement is even rarer and few cases involving the nasal cavity have been reported in the literature. Case Report. MES, a 54-year-old woman, complaining of progressive nasal obstruction and mild epistaxis through the right nostril which had developed 1 year previously. Computed tomography scan showed tumor with heterogeneous contrast enhancement occupying the right nasal cavity, moving contralaterally in the nasal septum. Excisional biopsy was performed through endoscopic surgery of the mass that was inserted at the nasal septum. Pathological and immunohistochemical exams concluded myoepithelioma. Discussion. The main symptoms of nasal myoepitheliomas are nasal obstruction and epistaxis. Immunohistochemistry is necessary to confirm the diagnosis, typically positive for cytokeratin and S-100, calponin, smooth muscle actin, myosin, vimentin, glial fibrillary acidic protein (GFAP), and carcinoembryonic antigen. The main marker for myoepithelioma is the S-100 protein. In our case, it was positive for cytokeratin, S-100, calponin, actin smooth muscle, and GFAP. In all cases reported in the literature surgical treatment was performed and the recurrence was associated with incomplete tumor resection. Final Comments. The myoepithelioma is a rare differential diagnosis of nasal tumors and its treatment is the total lesion excision.

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Section: Discussionmentioning

confidence: 99%

Myoepithelioma of the Nasal Septum: A Rare Case of Extrasalivary Gland Involvement

Cunha

Camurugy

Ribeiro

et al. 2017

Case Reports in Otolaryngology

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Myoepithelioma of the Parotid Gland: A Case Report with Review of the Literature and Classic Histopathology

Weitzel

Cohn

Spector

2017

Case Reports in Otolaryngology

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Myoepithelioma is a rare salivary gland neoplasm. They most commonly affect the major and minor salivary glands with the parotid gland being the most common, approximately 40%. Only 1% of all salivary gland neoplasms are myoepitheliomas. Myoepithelioma is usually a benign tumor arising from neoplastic myoepithelial or basket cells which are found between the basement membrane and the basal plasma membrane of acinar cells. They also contain multiple cellular elements. We present a case of a 73-year-old female with myoepithelioma of the parotid gland, an extremely rare neoplasm. There have been approximately 42 cases reported through 1985 and fewer than 100 cases through 1993. We will discuss the clinical presentation, pathophysiology, diagnosis, and treatment of such neoplasms.

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Voluminous Myoepithelioma of the Minor Salivary Glands Involving the Base of the Tongue

Cited by 2 publications

References 10 publications

Myoepithelioma of the Nasal Septum: A Rare Case of Extrasalivary Gland Involvement

Myoepithelioma of the Nasal Septum: A Rare Case of Extrasalivary Gland Involvement

Myoepithelioma of the Parotid Gland: A Case Report with Review of the Literature and Classic Histopathology

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