Volumetric study of the maxillary sinus in patients with sinus pathology

Pérez‐Sayáns, Mario; Quintanilla, Juan Antonio Suárez; Chamorro-Petronacci, Cintia; Suárez-Peñaranda, José Manuel; Jornet, Pía López; García, Francisco Gómez; Sánchez, Yolanda Guerrero

doi:10.1371/journal.pone.0234915

Cited by 13 publications

(7 citation statements)

References 31 publications

(38 reference statements)

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“…On the other hand, albeit in the bivariate and univariate analyses the maximum MS height > 33.60 mm and the atrophic/partially atrophic status of the alveolar process contributed significantly to the prevalence of mucosal thickenings, a confounding effect was evident after adjusting for other covariates in the final logistic regression model, as these parameters did not reach a significant association. Although these results partially coincide with those of other studies which indicate that the sinus size or volume [ 37 ] and the crest type [ 23 , 51 ] do not have an independent relationship with the mucosal thickenings, since the confounding occurs when there are shared causes among the exposure and an outcome, it would be feasible to deduce that the heterogeneous effects of the male gender condition, aging, the increased depth and volume of MS, as well as the presence of antroliths, may be important modifiers for the impact of the increased MS height or the atrophic/partially atrophic status of the alveolar process for its association with thickened mucosal status.…”

Section: Discussionsupporting

confidence: 92%

Analysis of risk variables for association with maxillary sinus mucosal thickenings: a cone-beam computed tomography-based retrospective study

et al. 2023

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Purpose This study aimed to determine which patient-related, anatomical, pathologic, or iatrogenic variables may be directly associated with and which may have a modifying effect on the generation of maxillary sinus (MS) mucosal thickenings. Methods A total of 278 cone-beam computed tomography (CBCT) scans obtained from 114 males and 164 females were evaluated. The protocol included the assessment of 21 candidate variables, of which 18 were bilateral and 3 were unique. The relationship among the study variables and the mucosal thickenings were examined individually and adjusted for confounding using univariate and multivariate binary logistic regression models. Results The prevalence of mucosal thickenings was 71.20% at patient level and 53.40% at sinus level. The ostium height > 28.15 mm, the infundibulum length ≤ 9.55 mm, the infundibulum width ≤ 0.50 mm, along the occurrence of periapical lesions and slight-to-severe periodontal bone loss acted as strong/independent risk variables for MS mucosal thickenings. Confounding and interaction relationships between MS height and depth, and between the alveolar process type and the presence of foreign materials with respect to age stratum > 47.50 years might be also associated with the mucosal thickenings. Conclusions While increased ostium height, decreased infundibulum length/width, the presence of periapical lesions and periodontal involvement might be the foremost indicator variables for MS mucosal thickenings, there are synergistic relationships among the increased sinus height and depth as well as aging regarding atrophic/partially atrophic alveolar process status and the presence of foreign materials that may be also associated with a greater proportion of these mucosal abnormalities.

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Section: Discussionsupporting

confidence: 92%

Analysis of risk variables for association with maxillary sinus mucosal thickenings: a cone-beam computed tomography-based retrospective study

et al. 2023

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“…A decrease in maxillary sinus volume has been associated with chronic pathological conditions such as rhinosinusitis 6 , 7 .…”

Section: Discussionmentioning

confidence: 99%

“…Nasal obstruction, whether resulting from chronic rhinosinusitis, infection, or other organic problems such as severe septal deviation, interferes with craniofacial skeletal development, alters olfactory function and taste, and leads to abnormal compensatory tongue posture 1 – 5 . The volume of the maxillary sinus has also been found to be affected by the pathophysiological state of the sinus epithelium; previous studies have reported that patients with chronic rhinosinusitis tend to have a smaller maxillary sinus volume 6 , 7 . However, the mechanism by which the bony sinus wall is remodeled under healthy or diseased epithelium remains unknown.…”

Section: Introductionmentioning

confidence: 99%

Craniofacial and olfactory sensory changes after long-term unilateral nasal obstruction—an animal study using MMP-3-LUC transgenic rats

Hsu,

Ratanasereeprasert,

Wang

et al. 2024

Sci Rep

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Nasal obstruction exerts considerable physiological effects on the respiratory system and craniofacial morphology during the developmental stage. This study used MMP-3-LUC transgenic rats for in vivo tracking of long-term expression in the rat nasal region after unilateral nasal obstruction. Skeletal changes of the craniofacial, nasal, and sinus regions were measured through micro-computed tomography examination and analysis with 3D image processing and calculation. Matrix metalloproteinase-3 and olfactory marker protein expression were also investigated through immunohistochemistry (IHC). Unilateral nasal obstruction significantly reduced the MMP-3 signal in the nasal region of MMP-3-LUC transgenic rats, which was mainly expressed in the respiratory epithelium. Long-term obstruction also caused morphological changes of the craniofacial hard tissue, such as nasal septal deviation, longer inter-jaw distance, and increased maxillary molar dental height. It also caused compensatory growth in olfactory nerve bundles and the olfactory epithelium, as confirmed by IHC. In our study, long-term unilateral nasal obstruction caused nasal septal deviation toward the unobstructed side, hyper divergent facial development including longer molar dental height, and reduced MMP-3 production. However, further investigation is necessary to explore the mechanism in depth.

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“…Earlier studies have investigated the linear dimensions of ITH and correlated them with SDA ( Chiesa Estomba et al, 2015 ). Recent studies have revealed that volumetric measurements are more accurate in demonstrating the extent of the pathology compared to the linear measurements ( Clarke et al, 2012 ; Pérez Sayáns et al, 2020 ). In the present study we have determined the volume of ITH and associated it with NSD.…”

Section: Discussionmentioning

confidence: 99%

Analysis of inferior nasal turbinate volume in subjects with nasal septum deviation: a retrospective cone beam tomography study

Shetty

Al-Bayatti

Alam

et al. 2022

PeerJ

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Background The association of the linear dimensions of the inferior turbinate hypertrophy with nasal septal deviation has been studied recently. However, the volumetric dimensions provide a more accurate status of the turbinate hypertrophy compared to linear measurements. The aim of this study was to analyze the association of inferior nasal turbinate volume with the degree of nasal septal deviation (NSD). Methods A retrospective evaluation of the cone beam computed tomography (CBCT) scans of 412 patients was carried out to obtain 150 scans which were included in the study. The scans were categorized into three groups. Group 1 comprised of 50 scans of patients with no inferior turbinate hypertrophy (ITH) and no nasal septal deviation. Group 2 comprised of 50 scans of patients with ITH and no NSD; whereas Group 3 included 50 scans of patients with ITH and NSD. The total turbinate volume of inferior turbinates (bilateral) were determined by using Vesalius 3D software (PS-Medtech, Amsterdam, Netherlands). Results The intraclass correlation coefficient (ICC) between the volumetric estimations performed by the two radiologists was 0.82. There were no significant age and gender related changes in the total turbinate volume. Patients in Group 3 had significantly higher (p = 0.001) total turbinate volume compared to Group 2 and Group 1. There was a positive and significant correlation (r = 0.52, p = 0.002) between the degree of septal deviation and total turbinate volume. When the total turbinate volume of the patients with different types of septal deviation was compared in Group 3, a statistically significant difference (p = 0.001) was observed. Regression analysis revealed that the septal deviation angle (SDA) (p = 0.001) had a relationship with total turbinate volume. From the results of the study we can conclude that the total turbinate volume is higher in patients with nasal septal deviation. It can also be concluded that the septal deviation angle has a positive correlation with total turbinate volume. The data obtained from the study can be useful in post-surgical follow up and evaluation of patients with nasal septal deviation and hypertrophied inferior nasal turbinate.

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Volumetric study of the maxillary sinus in patients with sinus pathology

Cited by 13 publications

References 31 publications

Analysis of risk variables for association with maxillary sinus mucosal thickenings: a cone-beam computed tomography-based retrospective study

Analysis of risk variables for association with maxillary sinus mucosal thickenings: a cone-beam computed tomography-based retrospective study

Craniofacial and olfactory sensory changes after long-term unilateral nasal obstruction—an animal study using MMP-3-LUC transgenic rats

Analysis of inferior nasal turbinate volume in subjects with nasal septum deviation: a retrospective cone beam tomography study

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