Volumetric Measurement for Comparison of the Accuracy between Intraoperative CT and Postoperative MR Imaging in Pituitary Adenoma Surgery

Lee, C.-C.; Lee, S.-T.; Chang, C.-N.; Pai, Ping‐Ching; Chen, Y.-L.; Hsieh, T’sang‐T’ang; Chuang, Chi‐Cheng

doi:10.3174/ajnr.a2506

Cited by 14 publications

(4 citation statements)

References 38 publications

(45 reference statements)

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“…compared the slicer software with the ellipsoid-based method in diffuse pediatric pontine glioma and suggested that the volume calculated slice-by-slice using the slicer software was more suitable for complex-shaped tumors. In our department, we have employed the OsiriX software for a long time and we believe in its accuracy56. Therefore, in addition to comparing the OsiriX software with the traditional method, we compared and discussed the performance of the OsiriX and slicer methods in estimating the tumor volume, especially for irregular-shaped tumors, which are mostly encountered in postoperative scenarios.…”

Section: Discussionmentioning

confidence: 99%

Different Volumetric Measurement Methods for Pituitary Adenomas and Their Crucial Clinical Significance

Chuang

Lin

Pai

et al. 2017

Sci Rep

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Confirming the status of residual tumors is crucial. In stationary or spontaneous regression cases, early treatments are inappropriate. The long-used geometric calculation formula is 1/2 (length × width × height). However, it yields only rough estimates and is particularly unreliable for irregularly shaped masses. In our study, we attempted to propose a more accurate method. Between 2004 and 2014, 94 patients with pituitary tumors were enrolled in this retrospective study. All patients underwent transsphenoidal surgery and received magnetic resonance imaging (MRI). The pre- and postoperative volumes calculated using the traditional formula were termed A1 and A2, and those calculated using the proposed method were termed O1 and O2, respectively. Wilcoxon signed rank test revealed no significant difference between the A1 and O1 groups (P = 0.1810) but a significant difference between the A2 and O2 groups (P < 0.0001). Significant differences were present in the extent of resection (P < 0.0001), high-grade cavernous sinus invasion (P = 0.0312), and irregular shape (P = 0.0116). Volume is crucial in evaluating tumor status and determining treatment. Therefore, a more scientific method is especially useful when lesions are irregularly shaped or when treatment is determined exclusively based on the tumor volume.

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Section: Discussionmentioning

confidence: 99%

Different Volumetric Measurement Methods for Pituitary Adenomas and Their Crucial Clinical Significance

Chuang

Lin

Pai

et al. 2017

Sci Rep

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show abstract

“…Additionally, according to our previous report26, the extent of resection could be assessed as reliably with intraoperative CT as with post-operative MRI. As a result, the degree of sella clearance, tumor resection ratio, and GTR/STR status could be determined via imaging as well as during the operation.…”

Section: Discussionmentioning

confidence: 99%

“…To establish and standardize the average volume of the normal pituitary gland and the granulation tissue after GTR of a pituitary adenoma, we calculated the average volume of the residual pituitary gland and granulation tissue, which was regarded as the baseline value and ranged between 0.20 and 0.40 cm 3 (mean ± 2SD). These data were obtained from 12 GTR patients in our previous report who were followed up for a long period after transsphenoidal pituitary surgery26.…”

Section: Methodsmentioning

confidence: 99%

Prediction of Long-term Post-operative Testosterone Replacement Requirement Based on the Pre-operative Tumor Volume and Testosterone Level in Pituitary Macroadenoma

Lee

Chen

Lee

et al. 2015

Sci Rep

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Non-functioning pituitary macroadenomas (NFPAs) are the most prevalent pituitary macroadenomas. One common symptom of NFPA is hypogonadism, which may require long-term hormone replacement. This study was designed to clarify the association between the pre-operative tumor volume, pre-operative testosterone level, intraoperative resection status and the need of long-term post-operative testosterone replacement. Between 2004 and 2012, 45 male patients with NFPAs were enrolled in this prospective study. All patients underwent transsphenoidal surgery. Hypogonadism was defined as total serum testosterone levels of <2.4 ng/mL. The tumor volume was calculated based on the pre- and post-operative magnetic resonance images. We prescribed testosterone to patients with defined hypogonadism or clinical symptoms of hypogonadism. Hormone replacement for longer than 1 year was considered as long-term therapy. The need for long-term post-operative testosterone replacement was significantly associated with larger pre-operative tumor volume (p = 0.0067), and lower pre-operative testosterone level (p = 0.0101). There was no significant difference between the gross total tumor resection and subtotal resection groups (p = 0.1059). The pre-operative tumor volume and testosterone level impact post-operative hypogonadism. By measuring the tumor volume and the testosterone level and by performing adequate tumor resection, surgeons will be able to predict post-operative hypogonadism and the need for long-term hormone replacement.

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“…On the contrary, intraoperative neuroimages are images that obtained intraoperatively and can be exported regularly to the navigation system. The intraoperative images can be obtained by using either intraoperative CT (iCT), MRI (iMRI) or ultrasound [3D-iUS) [1][2][3]. Safer and successful brain tumors surgery requires not only neuroimages-guided surgery but also properly defined the eloquent (important and functional) cortices and monitoring of the vital areas of the brain and other organs.…”

Section: Introductionmentioning

confidence: 99%

Functional MRI, Diffusion Tensor Imaging, Magnetic Source Imaging and Intraoperative Neuromonitoring Guided Brain Tumor Resection in Awake and Under General Anaesthesia

Idris¹,

Hassan²,

Mustapha³

et al. 2013

Clinical Management and Evolving Novel Therapeutic Strategies for Patients With Brain Tumors

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Volumetric Measurement for Comparison of the Accuracy between Intraoperative CT and Postoperative MR Imaging in Pituitary Adenoma Surgery

Cited by 14 publications

References 38 publications

Different Volumetric Measurement Methods for Pituitary Adenomas and Their Crucial Clinical Significance

Different Volumetric Measurement Methods for Pituitary Adenomas and Their Crucial Clinical Significance

Prediction of Long-term Post-operative Testosterone Replacement Requirement Based on the Pre-operative Tumor Volume and Testosterone Level in Pituitary Macroadenoma

Functional MRI, Diffusion Tensor Imaging, Magnetic Source Imaging and Intraoperative Neuromonitoring Guided Brain Tumor Resection in Awake and Under General Anaesthesia

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