2021
DOI: 10.1016/j.tige.2020.08.001
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Volumetric Laser Endomicroscopy in Barrett's Esophagus

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Cited by 2 publications
(3 citation statements)
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“…Volumetric laser endomicroscopy (VLE) is an advanced imaging method that applies the principles of optical coherence tomography. 32 In an observational study conducted by Smith et al, 33 VLE-guided biopsy improved, compared to random biopsies, the detection of BERN by 700% in cases where with other imaging methods no visual cues for neoplasia had been detected. However, the application of VLE and the interpretation of acquired information require practice and experience.…”
Section: Current Statusmentioning
confidence: 98%
“…Volumetric laser endomicroscopy (VLE) is an advanced imaging method that applies the principles of optical coherence tomography. 32 In an observational study conducted by Smith et al, 33 VLE-guided biopsy improved, compared to random biopsies, the detection of BERN by 700% in cases where with other imaging methods no visual cues for neoplasia had been detected. However, the application of VLE and the interpretation of acquired information require practice and experience.…”
Section: Current Statusmentioning
confidence: 98%
“…VLE uses a laser probe within a balloon catheter to circumferentially evaluate a 6 cm segment of the esophagus to a depth of 3 mm and a resolution of 7 to 10 μm. 35 It allows for two-dimensional cross-sectional images of all four layers of the esophagus at 10 times the resolution of an endoscopic ultrasound. At 7 to 10 μm, it can visualize glands, crypts, and villi, but not cellular features.…”
Section: Optical Coherence Tomographymentioning
confidence: 99%
“…Additionally, VLE alone may be limited by cost, commercial availability, lack of standardized protocol for image interpretation, and the need for additional training to develop competency in VLE interpretation (Table 1). 35,42,43 However, recent advancements in VLE technology such as CAD, IRIS, and laser marking have shown promising results and may offer a diagnostic benefit for detection of BE-related dysplasia in the future.…”
Section: Application Of Ai In Vlementioning
confidence: 99%