Volumetric evaluation of fluid responsiveness using a modified passive leg raise maneuver during experimental induction and correction of hypovolemia in anesthetized dogs

Paranjape, Vaidehi V.; Henao-Guerrero, Natalia; Menciotti, Giulio; Saksena, Siddharth

doi:10.1016/j.vaa.2023.02.009

Cited by 6 publications

(16 citation statements)

References 28 publications

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“…Even though PATD is considered the de facto ‘gold standard’ in human and veterinary medicine [ 8 , 9 , 33 , 36 , 37 ], it is linked with well-known limitations [ 44 ] and complications [ 10 ]. The factors contributing to measurement errors and variability include injectate volume and temperature, intracardiac shunts, valvular dysfunction, catheter dead space, injection time, irregular respiratory patterns, concurrent IV infusions, and exogenous cooling or warming [ 44 ].…”

Section: Discussionmentioning

confidence: 99%

“…Using a literature search of veterinary studies comparing CO measurement techniques with the gold standard PATD [ 33 , 36 , 37 ], an a priori power analysis indicates that a sample size of six dogs is necessary to show a minimum 20% significant difference in CO during the induction of acute changes in hemodynamics carried out by the manipulation of blood volume, assuming a statistical power of 0.8 and an alpha level of 0.05 ( accessed on 1 September 2021).…”

Section: Methodsmentioning

confidence: 99%

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Agreement between Electrical Cardiometry and Pulmonary Artery Thermodilution for Measuring Cardiac Output in Isoflurane-Anesthetized Dogs

Paranjape

Henao-Guerrero

Menciotti

et al. 2023

Animals

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In animals, invasive pulmonary artery thermodilution (PATD) is a gold standard for cardiac output (CO) monitoring, but it is impractical in clinical settings. This study evaluates the agreement between PATD and noninvasive electrical cardiometry (EC) for measuring CO and analyzes the other EC-derived hemodynamic variables in six healthy anesthetized dogs subjected to four different hemodynamic events in a sequential order: (1) euvolemia (baseline); (2) hemorrhage (33% blood volume loss); (3) autologous blood transfusion; and (4) 20 mL/kg colloid bolus. The CO measurements obtained using PATD and EC are compared using Bland–Altman analysis, Lin’s concordance correlation (LCC), and polar plot analysis. Values of p < 0.05 are considered significant. The EC measurements consistently underpredict the CO values as compared with PATD, and the LCC is 0.65. The EC’s performance is better during hemorrhage, thus indicating its capability in detecting absolute hypovolemia in clinical settings. Even though the percentage error exhibited by EC is 49.4%, which is higher than the standard (<30%), EC displays a good trending ability. Additionally, the EC-derived variables display a significant correlation with the CO measured using PATD. Noninvasive EC may have a potential in monitoring trends in hemodynamics in clinical settings.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Agreement between Electrical Cardiometry and Pulmonary Artery Thermodilution for Measuring Cardiac Output in Isoflurane-Anesthetized Dogs

Paranjape

Henao-Guerrero

Menciotti

et al. 2023

Animals

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“…However, in this investigation, the dogs were also mechanically ventilated and had received an NMBA. 57 In summary, in order to treat hypotension secondary to bradycardia, we administered a dose of 10 μg/kg terbutaline IV. This worsened the hypotension present.…”

Section: Discussionmentioning

confidence: 99%

“…Recently, another technique not reliant on heart‐lung interactions, the modified passive leg‐raising manoeuvre, was suggested to be useful in identifying hypovolaemic pig and dogs under general anaesthesia 57,58 . In the canine study, cardiac output significantly increased after raising the pelvic limbs, and the plethysmographic variability index and PPV significantly decreased.…”

Section: Discussionmentioning

confidence: 99%

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Management of severe hypotension in a dog undergoing transvenous pacemaker implantation following acepromazine and subsequent terbutaline administration

Alvarez

Bruniges

2023

Vet Record Case Reports

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This case report describes events that occurred under general anaesthesia of a dog undergoing transvenous pacemaker implantation for third‐degree atrioventricular block. Following premedication with acepromazine and buprenorphine, general anaesthesia was induced with alfaxalone, and maintained with isoflurane in oxygen. The dog developed severe hypotension during the procedure with concurrent bradycardia before commencement of pacing. In order to increase the heart rate, terbutaline was administered intravenously. This was followed by a worsening of the hypotension, with only a small increase in heart rate. Blood pressure improved following noradrenaline infusion. The animal recovered uneventfully in intensive care, and was sedated due to its anxious temperament to avoid dislodgement of the pacemaker device in the postoperative period.

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Cardiac Output Measurement

Vigani

2024

Veterinary Anesthesia and Analgesia

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Volumetric evaluation of fluid responsiveness using a modified passive leg raise maneuver during experimental induction and correction of hypovolemia in anesthetized dogs

Cited by 6 publications

References 28 publications

Agreement between Electrical Cardiometry and Pulmonary Artery Thermodilution for Measuring Cardiac Output in Isoflurane-Anesthetized Dogs

Agreement between Electrical Cardiometry and Pulmonary Artery Thermodilution for Measuring Cardiac Output in Isoflurane-Anesthetized Dogs

Management of severe hypotension in a dog undergoing transvenous pacemaker implantation following acepromazine and subsequent terbutaline administration

Cardiac Output Measurement

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