Volumetric and acoustic studies of aqueous l-arginine·HCl and l-proline in electrolytic and non-electrolytic solutions at various temperatures

John, Rojo; Tangde, Vijay M.; Khaty, Niraj T.; Dhondge, Alka S.; Dhondge, Sudhakar S.

doi:10.1016/j.jics.2022.100370

Cited by 3 publications

(1 citation statement)

References 43 publications

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“…To ascertain the reliability of the experimental setup and obtain ρ and u data, measurements of aqueous l -proline and l -valine solutions were undertaken, and a comparative analysis was conducted with the available literature. As depicted in Figures S1–S4 (Supporting Information), the obtained experimental data are in excellent agreement with the values reported earlier by the other authors. − The precision of the measurements, as specified by the manufacturer, is 0.01 m·s –1 for speed of sound measurements and 0.001 kg·m –3 for density measurements. However, to consider the discrepancies resulting from systematic errors, the standard uncertainties were estimated using 10 consecutive measurements of a single solute concentration across all of the reported temperatures, i.e., ( T = 288.15–318.15) K. The standard deviation (σ) was determined from the resulting experimental data employing expression σ = { ∑ ( F false( x exp false) − F false( x normala normalv normale normalr normala normalg normale false) ) 2 ( n − 1 ) } 1 / 2 where n denotes the number of experimental points.…”

Section: Methodssupporting

confidence: 88%

Unraveling the Solvation Behavior of Levocetirizine Dihydrochloride: Insights from Volumetric, Acoustic, Viscometric, and Electronic Absorption Studies in Aqueous l-Proline and l-Valine Solutions

Umredkar,

Tangde,

Khaty

et al. 2024

J. Chem. Eng. Data

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The present article delves into the solvation behavior of levocetirizine dihydrochloride (LCTZ) in aqueous environments, thoroughly examining its interactions with two primary amino acids, L-proline and L-valine. This study spans the entire human body temperature range of 288.15−318.15 K, shedding light on the molecular dynamics and properties of LCTZ in the presence and absence of these amino acids. The investigation explores the volumetric, acoustic, viscometric, and electronic absorption properties of the system, along with extensive calculations of various thermodynamic and transport parameters of significance. The preponderance of hydrophobic associations of LCTZ with the water structure along with the dominant amino acid−LCTZ interaction surfaces out of the volumetric analysis, wherein viscometric and compressibility studies offer further support to the speculation. In the same vein, the sign of the temperature derivative of the B coefficient as well as that of Hepler's constant underscores the chaotropic trait of studied molecules. The research thus contributes to a comprehensive understanding of intricate associations between LCTZ and the amino acids, unveiling the plausible intermolecular phenomenon for potential applications in drug delivery platforms. In this investigation, an attempt has been made to fill the gap in the existing literature, opening avenues for further research in this area.

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Section: Methodssupporting

confidence: 88%

Unraveling the Solvation Behavior of Levocetirizine Dihydrochloride: Insights from Volumetric, Acoustic, Viscometric, and Electronic Absorption Studies in Aqueous l-Proline and l-Valine Solutions

Umredkar,

Tangde,

Khaty

et al. 2024

J. Chem. Eng. Data

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The Effect of Temperature on the Volume Properties of L-Lysine in Aqueous and Aqueous Buffer Solutions

Tyunina

Тарасова

2023

Russ. J. Phys. Chem.

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The Effect of Temperature on the Volume Properties of L-Lysine in Aqueous and Aqueous Buffer Solutions

Tyunina,

Tarasova

2023

Russian Journal of Physical Chemistry

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The behavior of L-lysine (Lys) in water and an aqueous buffer solution is studied by densimetry as the temperature varies from 288.15 to 313.15 K with an interval of 5 K. Based on the experimental density values of amino-acid solutions, the apparent molar volumes and partial molar volumes of Lys are determined at an infinite dilution in water and buffer solution at each temperature. The effects of temperature, medium, and amino-acid concentration on volumetric characteristics are revealed. The partial molar extensibility and their derivatives with respect to temperature, the values of which indicate the structurally destructive behavior of Lys in the studied solutions, are determined. It is found that the structurally destructive effects of Lys are enhanced in an aqueous buffer solution. It is shown that the partial molar volumes of amino-acid transfer from water to the buffer solution have positive values in the studied temperature range. The results obtained are discussed on the basis of various types of molecular interactions between a solute and a solvent using the Gurney model.

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Volumetric and acoustic studies of aqueous l-arginine·HCl and l-proline in electrolytic and non-electrolytic solutions at various temperatures

Cited by 3 publications

References 43 publications

Unraveling the Solvation Behavior of Levocetirizine Dihydrochloride: Insights from Volumetric, Acoustic, Viscometric, and Electronic Absorption Studies in Aqueous l-Proline and l-Valine Solutions

Unraveling the Solvation Behavior of Levocetirizine Dihydrochloride: Insights from Volumetric, Acoustic, Viscometric, and Electronic Absorption Studies in Aqueous l-Proline and l-Valine Solutions

The Effect of Temperature on the Volume Properties of L-Lysine in Aqueous and Aqueous Buffer Solutions

The Effect of Temperature on the Volume Properties of L-Lysine in Aqueous and Aqueous Buffer Solutions

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