Volume of whole blood and absolute amount of serum proteins in the early stage of late toxemia of pregnancy

Physiological adaptation of maternal plasma volume during pregnancy: a systematic review and meta-analysis

“…Plasma volume begins to increase from as early as the first weeks in pregnancy, has its steepest increase during the 45 Raman (1985) 9 Blekta (1970) 35 Brody (1967) 36 Brody (1967) 36 NA for single study…”

“…The expansion in both of these studies was lower when compared with the expansions estimated in physiological pregnancies during the same gestational intervals. Five studies measured plasma volume in pregnancies with a hypertensive pregnancy complication (PIH and PE) 9,35,36,45,50 and one study measured plasma volume in pregnancies complicated by FGR 2 between 36 and 40 weeks' gestation. Egger's regression test for funnel plot asymmetry was not statistically significant (P = 0.76).…”

“…The pooled estimate of plasma volume expansion in complicated pregnancies at 36-41 weeks was 0.80 L (95% CI, 0.59-1.02 L) (32.3% (95% CI, 23.6-41.1%)) compared with the reference value, which was statistically significantly smaller, by 13.3% (P < 0.0001), than the 1.13 L expansion in physiological pregnancies during the same gestational period (Figure 4). 38 Whittaker (1996) 38 Whittaker (1993) 37 Whittaker (1993) 37 Abudu (1985) 14 Taylor (1979) 33 Pirani (1973) 7 Blekta (1970) 35 Hytten (1963) 5 Hytten (1963) 5 Paintin (1962) 27 Berlin (1953) 39 Berlin (1953) 39 Berlin (1953) 39 Berlin (1953) 39 Summary…”

“…Vargas (2007) 40 Whittaker (1996) 38 Whittaker (1993) 37 Abudu (1988) 30 Abudu (1985) 14 Rajalakshmi (1985) 32 Bruinse (1985) 44 Hunyor (1982) 46 Pirani (1973) 7 Pirani (1973) 7 Blanche Butler (1968) 34 Hytten (1963) 5 Paintin (1962) 27 Berlin (1953) 39 Whittaker (1996) 38 Whittaker (1993) 37 Bruinse (1985) 44 Rajalakshmi (1985) 32 Abudu (1985) 14 Gibson (1973) 47 Pirani (1973) 7 Blekta (1970) 35 Blanche Butler (1968) 34 Rovinsky (1965) 51 Hytten (1963) 5 Hytten (1963) 5 Berlin (1953) 39 Berlin (1953) Only first author of each study is given. Some studies appear more than once within a gestational-age interval because they provided data for different gestational weeks within that interval.…”

“…Olufemi (1991) 43 5 70 Bruinse (1985) 44 Rajalakshmi (1985) 32 Abudu (1985) 14 Pirani (1973) 7 Pirani (1973) 7 Brody (1967) 36 Rovinsky (1965) 51 Rovinsky (1965) 51 Hytten (1963) 5 Paintin (1962) 27 Berlin (1953) 39 Berlin (1953) 39 Vargas (2007) 40 Whittaker (1996) 38 Whittaker (1993) 37 Whittaker (1993) 37 Abudu (1988) 30 Raman (1985) 9 Rajalakshmi (1985) 32 Abudu (1985) 14 Hunyor (1984) 45 Hunyor (1982) 46 Taylor (1979) 33 Pirani (1973) 7 Gibson (1973) 47 Stimson (1972) 48 Blekta (1970) 35 Blanche Butler (1968) 34 Blanche Butler (1968) 34 Brody (1967) 36 Brody (1967) 36 Rovinsky (1965) 51 Hytten (1963) 5 Paintin (1962) 27 McLennan (1950) 31 McLennan (1950) 31 McLennan (1948) 23 Dieckmann (1934) 29 Salas (1993) 2 Whittaker (1996) 38 Pivarnik (1994) 42 Hytten (1963) 5 Hønger (1968) 49 Hønger ( Only first author of each study is...…”