Volume loss in the left anterior‐superior subunit of the hypothalamus in amyotrophic lateral sclerosis
Sadegh Ghaderi,
Farzad Fatehi,
Sanjay Kalra
et al.
Abstract:Background and ObjectiveAmyotrophic lateral sclerosis (ALS) causes motor neuron loss and progressive paralysis. While traditionally viewed as motor neuron disease (MND), ALS also affects non‐motor regions, such as the hypothalamus. This study aimed to quantify the hypothalamic subregion volumes in patients with ALS versus healthy controls (HCs) and examine their associations with demographic and clinical features.MethodsForty‐eight participants (24 ALS patients and 24 HCs) underwent structural MRI. A deep conv… Show more
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