Volume and morphology of left atrial appendage as determinants of stroke subtype in patients with atrial fibrillation

Jeong, Woojin; Choi, Jin‐Ho; Son, Jeong Pyo; Lee, Su-Yeon; Lee, Mi Ji; Choe, Yeon Hyeon; Bang, Oh Young

doi:10.1016/j.hrthm.2015.12.026

Cited by 35 publications

(24 citation statements)

References 23 publications

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“…For example, AF patients with the "chicken wing" type of left atrial appendage (LAA) morphology on multidetector cardiac computed tomography are reportedly less likely to have an embolic event after controlling for comorbidities and CHADS 2 score. 55 Both other 56 and our studies 57 have shown that the LAA volume and LAA orifice diameter are both greater in patients with AF-related stroke than in those with AF-unrelated stroke and those without AF ( Fig. 5 ).…”

Section: Advances In Diagnostic Techniques May Be Particularly Helpfusupporting

confidence: 57%

Considerations When Subtyping Ischemic Stroke in Asian Patients

Bang

2016

J Clin Neurol

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Both the incidence and prevalence of stroke in Asia are steadily increasing, and the burden of stroke is particularly high in Asian countries. Although strokes in Asians and Caucasians share many common features, there are some differences that are probably due to differences in lifestyle and genetic background. While there have been advances in the stroke classification system, the assignment of Asian stroke patients to etiological categories has received little attention. The current classification system may not be well suited to Asian patients with ischemic stroke because the proportions and relative importance of stroke subtypes may differ with race and ethnicity. This review addresses concerns about the use of the current stroke classification system in Asian patients with ischemic stroke, and proposes a classification system that is more specific to the Asian population, in conjunction with discussing advances in diagnostic techniques.

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Section: Advances In Diagnostic Techniques May Be Particularly Helpfusupporting

confidence: 57%

Considerations When Subtyping Ischemic Stroke in Asian Patients

Bang

2016

J Clin Neurol

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“…This implies that these parameters may be useful for discriminating AF-related stroke from AF-unrelated stroke in AF patients with a higher CHA 2 DS 2 -VASc score. A very recent multidetector cardiac computed tomography study showed that in patients with AF plus stroke, left atrial appendage orifice diameter and volume were determinants of cardiogenic embolic stroke and were useful for stratifying noncardioembolic risk [39]. …”

Section: Discussionmentioning

confidence: 99%

“…The patients were divided into AF-related and AF-unrelated stroke groups according to presumed stroke subtypes based on the criteria published by the Stroke Prevention in Atrial Fibrillation investigators with some modifications (Table 1) [7,8,9,10]. …”

Section: Methodsmentioning

confidence: 99%

Implications of CHA<sub>2</sub>DS<sub>2</sub>-VASc Score in Stroke Patients with Atrial Fibrillation: An Analysis of 938 Korean Patients

Hwang¹,

Chung²,

Lee³

et al. 2017

Eur Neurol

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Background and Aims: The aim of this study was to investigate the stroke mechanisms and associated conditions influencing the decision regarding stroke thromboprophylaxis in patients with atrial fibrillation (AF) plus ischemic stroke, according to the CHA₂DS₂-VASc score. Methods: We evaluated 938 consecutive patients with a diagnosis of AF plus transient ischemic attack/ischemic stroke. Based on the CHA₂DS₂-VASc scores, patients were stratified as score 0 or 1 (n = 151), score 2 (n = 146), score 3 (n = 213), score 4 (n = 185), or score ≥5 (n = 243). Results: Patients with a higher CHA₂DS₂-VASc score were more likely to have noncardioembolic stroke mechanism (p = 0.001). Large-artery atherosclerosis causing stenosis >50% was more frequently observed in the high CHA₂DS₂-VASc group (p < 0.001). Coronary artery disease and the use of antiplatelet agents were more prevalent in the higher group (p < 0.001). A high CHA₂DS₂-VASc score was associated with a higher frequency of cerebral microbleeds and a higher Fazekas grade for leukoaraiosis (p < 0.001). The HAS-BLED score was correlated with the CHA₂DS₂-VASc score (γ = 0.650; p < 0.001). Conclusions: A higher CHA₂DS₂-VASc score is associated with noncardioembolic mechanisms of stroke and with a higher risk of bleeding. Strategies to treat macro/microangiopathy such as use of statin for plaque stabilization, as well as oral anticoagulants with a lower bleeding risk, are needed in these patients.

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“…В одной из работ последних лет W.K.Jeong et al изучали морфофункциональные характеристики УЛП у пациентов с ФП и ОНМК в сравнении с идентичными параметрами, полученными при обследовании больных с ФП без мозговой катастрофы. По итогам анализа результатов обследований было показано, что увеличенный объем УЛП и расширенный диаметр его устья являются независимыми факторами риска развития кардиоэмболического инсульта [12].…”

Section: роль морфофункциональных особенностей ушка левого предсердияunclassified

Left atrial appendage thrombosis in atrial fibrillation - current status of the problem

Кривошеев¹,

Башта

Красильникова

et al. 2020

Vestnik aritmologii

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Volume and morphology of left atrial appendage as determinants of stroke subtype in patients with atrial fibrillation

Cited by 35 publications

References 23 publications

Considerations When Subtyping Ischemic Stroke in Asian Patients

Considerations When Subtyping Ischemic Stroke in Asian Patients

Implications of CHA<sub>2</sub>DS<sub>2</sub>-VASc Score in Stroke Patients with Atrial Fibrillation: An Analysis of 938 Korean Patients

Left atrial appendage thrombosis in atrial fibrillation - current status of the problem

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