Voltamperometric Sensors and Biosensors Based on Carbon Nanomaterials Used for Detecting Caffeic Acid—A Review

Bounegru, Alexandra Virginia; Apetrei, Constantin

doi:10.3390/ijms21239275

Cited by 26 publications

(17 citation statements)

References 202 publications

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“…Phenolic compounds are easy to determine and quantify with the aid of carbon-based sensors [ 142 ], and the electrochemical responses offer information on the reaction mechanism and the functional properties of the substance [ 143 , 144 , 145 , 146 ].…”

Section: Electrochemical Methods For Evaluating the Quality Of Olive Oilmentioning

confidence: 99%

Evaluation of Olive Oil Quality with Electrochemical Sensors and Biosensors: A Review

Bounegru

Apetrei

2021

IJMS

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Electrochemical sensors, sensor arrays and biosensors, alongside chemometric instruments, have progressed remarkably of late, being used on a wide scale in the qualitative and quantitative evaluation of olive oil. Olive oil is a natural product of significant importance, since it is a rich source of bioactive compounds with nutritional and therapeutic properties, and its quality is important both for consumers and for distributors. This review aims at analysing the progress reported in the literature regarding the use of devices based on electrochemical (bio)sensors to evaluate the bioactive compounds in olive oil. The main advantages and limitations of these approaches on construction technique, analysed compounds, calculus models, as well as results obtained, are discussed in view of estimation of future progress related to achieving a portable, practical and rapid miniature device for analysing the quality of virgin olive oil (VOO) at different stages in the manufacturing process.

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Section: Electrochemical Methods For Evaluating the Quality Of Olive Oilmentioning

confidence: 99%

Evaluation of Olive Oil Quality with Electrochemical Sensors and Biosensors: A Review

Bounegru

Apetrei

2021

IJMS

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“…The most popular target molecule is glucose for biometric health monitoring ( Table 2 ) [ 224 , 227 , 228 , 237 , 249 , 269 , 271 , 273 ]. However, biosensors have been developed to detect many other bioactive compounds too, such as cholesterol [ 312 , 370 , 371 ] and triglycerides [ 282 ], lactose [ 220 ] and lactate [ 225 , 280 ], neurotransmitters [ 234 , 240 , 246 , 278 , 279 , 372 ] and hormones [ 239 ], various disease biomarkers [ 244 , 257 , 261 ], microRNAs [ 223 ], drugs [ 218 , 287 ], pathogens [ 219 ] and toxins [ 221 ], xanthine [ 262 ] and caffeic acid [ 373 ], p -coumaric acid [ 232 ], ferulic acid [ 233 ], trace metals [ 274 ], and oxygen [ 268 ].…”

Section: Applications Of Cnm-enzyme Conjugatesmentioning

confidence: 99%

Carbon Nanomaterials (CNMs) and Enzymes: From Nanozymes to CNM-Enzyme Conjugates and Biodegradation

et al. 2022

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Carbon nanomaterials (CNMs) and enzymes differ significantly in terms of their physico-chemical properties—their handling and characterization require very different specialized skills. Therefore, their combination is not trivial. Numerous studies exist at the interface between these two components—especially in the area of sensing—but also involving biofuel cells, biocatalysis, and even biomedical applications including innovative therapeutic approaches and theranostics. Finally, enzymes that are capable of biodegrading CNMs have been identified, and they may play an important role in controlling the environmental fate of these structures after their use. CNMs’ widespread use has created more and more opportunities for their entry into the environment, and thus it becomes increasingly important to understand how to biodegrade them. In this concise review, we will cover the progress made in the last five years on this exciting topic, focusing on the applications, and concluding with future perspectives on research combining carbon nanomaterials and enzymes.

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“…Caffeic acid (CA) is a phenolic derivative generally found in green tea, red wine, fruits, vegetables, and coffee ( Chen et al, 2019 ; Meinhart et al, 2019 ; Zhang et al, 2019 ). CA (3,4-dihydroxycinnamic acid) exhibits anti-bacterial and anti-inflammatory effects and participates in significant functions of the human system ( Kępa et al, 2018 ; Bounegru and Apetrei, 2020 ). It demonstrates anti-cancer, anti-oxidant, anti-proliferative, and anti-inflammatory properties.…”

Section: Introductionmentioning

confidence: 99%

Potential Therapeutic Implications of Caffeic Acid in Cancer Signaling: Past, Present, and Future

et al. 2022

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Caffeic acid (CA) has been present in many herbs, vegetables, and fruits. CA is a bioactive compound and exhibits various health advantages that are linked with its anti-oxidant functions and implicated in the therapy and prevention of disease progression of inflammatory diseases and cancer. The anti-tumor action of CA is attributed to its pro-oxidant and anti-oxidant properties. CA’s mechanism of action involves preventing reactive oxygen species formation, diminishing the angiogenesis of cancer cells, enhancing the tumor cells’ DNA oxidation, and repressing MMP-2 and MMP-9. CA and its derivatives have been reported to exhibit anti-carcinogenic properties against many cancer types. CA has indicated low intestinal absorption, low oral bioavailability in rats, and pitiable permeability across Caco-2 cells. In the present review, we have illustrated CA’s therapeutic potential, pharmacokinetics, and characteristics. The pharmacological effects of CA, the emphasis on in vitro and in vivo studies, and the existing challenges and prospects of CA for cancer treatment and prevention are discussed in this review.

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Voltamperometric Sensors and Biosensors Based on Carbon Nanomaterials Used for Detecting Caffeic Acid—A Review

Cited by 26 publications

References 202 publications

Evaluation of Olive Oil Quality with Electrochemical Sensors and Biosensors: A Review

Evaluation of Olive Oil Quality with Electrochemical Sensors and Biosensors: A Review

Carbon Nanomaterials (CNMs) and Enzymes: From Nanozymes to CNM-Enzyme Conjugates and Biodegradation

Potential Therapeutic Implications of Caffeic Acid in Cancer Signaling: Past, Present, and Future

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