Voltammetric studies of titanium (IV) phosphate modified with copper hexacyanoferrate and electroanalytical determination of N-acetylcysteine

Abstract

Titanium (IV) Phosphate copper hexacyanoferrate composite (TiPhCuHCF) was prepared using a new methodology for the synthesis. A preliminary characterization of the precursor and resulting materials was defined using spectroscopic and chemical techniques. The cyclic voltammogram of the modified electrode containing TiPhCuHCF exhibited two redox couples. The first and second redox couples present a formal potential (E h 0 ) of 0.18 and 0.76 V and were ascribed to the Cu ?/ Cu 2? (E h 0 ) 1 and Fe 2? (CN) 6 /Fe 3? (CN) 6 (E h 0 ) 2 processes, respectively. In a preliminary study, the peak located at 0.76 V displays a sensitive response to N-acetylcysteine. The modified graphite paste electrode showed a linear range from 1.0 9 10 -5 to 7.0 9 10 -4 mol L -1 for the determination of N-acetylcysteine with a limit detection of 6.96 9 10 -5 mol L -1 and relative standard deviation of ± 5% (n = 3) and amperometric sensitivity of 24.79 9 10 -3 A mol L -1 . The modified electrode was electrochemically stable and showed good reproducibility.

The use of titanium (IV) phosphate for metal removal from aqueous and alcoholic samples

“…In a previous work [35], we report a complete characterization of TiPh and their use as an electrochemical sensor for the detection of n-acetylcysteine. Herein, we report its potential as an adsorbent composite for some transition metals such as copper (Cu +2 ), cobalt (Co +2 ) and nickel (Ni +2 ) in different media.…”

“…In previous investigation, we have prepared a titanium (IV) phosphate copper hexacyanoferrate composite from aqueous phosphoric acid and titanium (IV) isopropoxide (TiPh). The obtained hybrid material was fully characterized and displayed electrochemical stability with good reproducibility for the determination of N-acetylcysteine [35]. In this paper, the focus is placed on the synthesis of phosphate-modified TiO 2 and their adsorptive behavior toward different metallic species: Co +2 , Cu +2 , and Ni +2 .…”

Reactivity of a Silsesquioxane Organofunctionalized with 4-Amino-5-Phenyl-4H-[1,2,4]-Triazole-3-thiol: Complementary Characterization and an Application to Chronoamperometric Detection of L-Dopamine

“…The modified graphite paste electrodes were prepared by mixing the modified octakis(3-chloropropyl)octasilsesquioxane with graphite powder (20% w/w) and nujol oil [42]. The MGPE was packed into an electrode body, consisting of a glass tube of i.d.…”

“…A preliminary characterization (FT-IR) and a rigorous electrochemical study have been performed and published recently [41]. The compound 2 possesses S-C-N linkages and exhibits potential active sites for metal ions that may also be biologically active just like some other amineand thione-substituted trizoles [42]. Thus the compound 3 will behavior as a chelanting agent of Cu 2+ ions and compound 4 can provide a good electron shuttle between the substrate (i.e.…”

Preparation and Voltammetric Study of a Composite Titanium Phosphate/Nickel Hexacyanoferrate and Its Application in Dipyrone Determination

“…Electrodes chemically modified with titanium phosphate have arousing great interest in the area of electrochemistry (Bruque et al, 1995;Pipi et al, 2010) due to its easy preparation and quick renewal of the electrode surface. Many ways of anchoring compounds electrochemically active on the surface have been investigated in order to shorten the distance between the oxidation-reduction sites involved in electronic transfer reactions (Willner et al, 2000;Murray et al, 1984).…”