Voltammetric studies of nitrofuroxime

Abstract

The electrochemical reduction behavior of nitrofuroxime has been studied using dc pokarography, cyclic voltammetry, ac polarography, differential pulse polarography, millicoulometry, and controlled potential electrolysis in universal buffers of pH values ranging from 2.0 to 12.0 in DMF/water mixtures. Kinetic parameters such as diffusion coefficient and forward rate constant values are evaluated, and a reduction mechanism is proposed. A differential pulse polarographic method is developed for the quantitative determination of nitrofuroxime in pharmaceutical formulations. The method of standard additions is used. The relative standard deviation and correlation coefficient are 1.84% and 0.991, respectively.

Comportamento eletroquímico de nitrofuranos em eletrodos de diamante dopado com boro-modelo para o mecanismo de ação de nitrocompostos com atividades antichagásica

“…Usando o coeficiente de difusão relatado por Reddy et al[140], o número de elétrons aumentou para aproximadamente 7, Tabela 9. Este resultado pode ser considerado, já que alguns autores[139,141] mostraram que a redução do grupo…”