Voltammetric reduction of finasteride at mercury electrode and its determination in tablets

Electrochemical determination of closantel in the commercial formulation by square-wave adsorptive stripping voltammetry

“…Since organic molecules containing the carbonyl group (>C=O) in the free form are electrochemically reducible [17, 34, 35], it can be expected that the reduction of CLS, which includes a >C=O group in its chemical structure (Fig. 1), may also result in a similar voltammetric pattern.…”

“…Due to the fact that a method is viewed as incomplete and cannot be considered as reliable in routine use if no validation test was performed [35, 36], a robustness test in the validation procedure should be studied as part of the procedure development. Therefore, to establish the optimal conditions for voltammetric determination of CLS on Hg(Ag)FE, and to gain the knowledge about its redox behavior, thoroughgoing studies were carried out.…”

Advances in the analysis of steroid hormone drugs in pharmaceuticals and environmental samples (2004–2010)

“…For this reason and since mercury is considered to be a health hazard, this importance has recently further decreased. In spite of this, several papers have been published up to the present time based on dropping [126] or hanging [127] mercury electrodes. Two of these are mentioned here: the voltammetric determination of finasteride in tablets [126] and the assay of danazol capsules by square-wave adsorptive stripping voltammetry [127].…”

Electrochemical Sensors in Environmental Analysis

“…These methods are still considered as nonselective and non-stable indicating methods. 54 Few studies used mercury as dropping 55 or hanging 56 electrodes. The voltammetric determination of finasteride in tablets and the assay of danazol in capsules by square-wave adsorptive stripping voltammetry were already reported.…”