Voltammetric Determination of Nicotine at Poly(4‐Amino‐3‐Hydroxynaphthalene Sulfonic Acid)‐Modified Glassy Carbon Electrode

Abstract

A poly(4-amino-3-hydroxynaphthalene sulfonic acid)-modified glassy carbon electrode was developed for the voltammetric determination of nicotine. An oxidation signal at lower potential with higher current was obtained for nicotine at the polymer-modified electrode compared to bare glassy carbon electrode suggesting the electrocatalytic effect of the polymer film. Under optimum conditions, square wave voltammetry of nicotine showed oxidation at + 884 mV (vs. SCE) in phosphate buffer solution pH 7.5. The calibration curve was linear over the range 1.0 to 200.0 mM (R 2 = 0.9987) concentration of nicotine with a detection limit (S/N = 3) of 8.66 10 À7 mol L À1. Application of the proposed method to cigarette tobacco samples gave acceptable recovery results of 90.7 % to 107.2 %.

Voltammetric determination of nicotine in cigarette tobacco at electrochemically activated glassy carbon electrode

“…Comparison of the experimental values with the actual content of nicotine in the samples analyzed could not be made since the samples did not have a label claimed value. However, the results obtained are in the range where nicotine is typically available in tobacco leaves which is 2-8% of the dry weight [23]. The reliability of the method was also checked by recovery experiments under the optimized conditions by spiking known amounts of nicotine standard solutions to the previously analyzed cigarette samples.…”

“…Among few studies involving nanotubes, carbon nanotube cluster modified screen printed electrode [11], and glassy carbon electrode modified with multi-walled carbon nanotube [21] and multi-walled carbon nanotubes-alumina-coated silica nanocomposite [22] were reported as electrochemical nicotine sensors. Recently, the electrochemical oxidation and its analytical determination of nicotine at a new conducting polymer modified electrode was demonstrated [23]. In this work a simple, sensitive and costeffective voltammetric method for the determination of nicotine in phosphate buffer solution was developed using activated glassy carbon electrode (AGCE).…”

Rapid electrochemical platform for nicotine sensing in cigarettes and chewing gums

“…Nicotine ([3-(2S)-1-methylpyrrolidin-2-yl)pyridine) belongs to pyridine alkaloids obtained from the plant Nicotiana tabacum (Geto et al, 2012). This substance stimulates brain activity, increases the activity of smooth muscles or synthesis of endorfines and therefore can be used in therapy of some neurodegenerative processes (Stočes and Švancara, 2014).…”

“…Application of the proposed method to cigarette samples gave acceptable recovery results (Geto et al, 2012). Electrochemical behavior of nicotine was studied using carbon paste electrode.…”

Polymer-modified glassy carbon electrode for the electrochemical detection of quinine in human urine and pharmaceutical formulations

“…Recently, the application of poly(4-amino-3-hydroxynaphthalene sulfonic acid)-modified glassy carbon electrode (p-(AHNSA)/GCE) for the electrochemical determination of nicotine [21], theophyline [22], ephedrine [23], and caffeine [24] has been reported. The polymer film can be easily deposited on the electrode surface by electrooxidation of its monomer, and the modified electrodes have shown excellent electrocatalytic effects towards the compounds reported.…”