Voltammetric determination of cocaine in confiscated samples using a cobalt hexacyanoferrate film-modified electrode

Oiye, Érica Naomi; Figueiredo, Natália Biziak de; Andrade, José Fernando de; Tristão, Heloísa Maria; Oliveira, Marcelo Firmino de

doi:10.1016/j.forsciint.2009.08.004

Cited by 54 publications

(35 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, interferences from substances which oxidise at potentials close to that observed for cocaine make the analysis more difficult. This difficulty has sometimes been solved by the modification of the working electrode with polymers, Schiff bases, or biomolecules which increase the sensitivity and provide selectivity to the electrochemical system (Table 1) [29][30][31][32][33][34][35][36][37]. Comparing the analytical parameters with those previously reported in the literature (see Table 1), it is clearly seen that the use of the PANI-β-CD/ fMWCNT film leads, in most cases, to comparable limits of detection.…”

Section: Analytical Applicationmentioning

confidence: 92%

Carbon nanotube β-cyclodextrin-modified electrode for quantification of cocaine in seized street samples

Garrido

Borges

Brett

et al. 2016

Ionics

View full text Add to dashboard Cite

Detection and quantification of cocaine is a key tool in fields such as police apprehensions and the fight against drug trafficking. Thus, a simple, fast and inexpensive electroanalytical methodology for the determination of cocaine in seized street samples has been developed, employing linear sweep voltammetry. The method is based on the use of a glassy carbon (GC) electrode modified by a combination of multi-walled carbon nanotubes (MWCNT) with β-cyclodextrin (β-CD) incorporated in a polyaniline film. The proposed method shows high reproducibility, repeatability and specificity. Under optimal conditions, the β-CD/ MWCNT-modified GC electrode gives a detection limit of 1.02 μM cocaine. The results obtained are in good agreement with those obtained by the high-performance liquid chromatography reference method. The new methodology proposed has excellent potential as the basis of a portable analytical sensor for on-site screening of cocaine in seized street samples.

show abstract

Section: Analytical Applicationmentioning

confidence: 92%

Carbon nanotube β-cyclodextrin-modified electrode for quantification of cocaine in seized street samples

Garrido

Borges

Brett

et al. 2016

Ionics

View full text Add to dashboard Cite

show abstract

“…Electroanalytical techniques have often been used for the analysis of a wide range of substances of industrial, pharmacological, and biomedical interest [14][15][16]23]. Voltammetry, for instance, consists in the application of a linear ramp of electrical potential between two electrodes (working and auxiliary) immersed in a liquid solution containing an analyte, with subsequent measurement of the produced electric current [20].…”

Section: Electroanalytical Methodologiesmentioning

confidence: 99%

Voltammetric determination of Δ9-THC in glassy carbon electrode: An important contribution to forensic electroanalysis

Balbino

Menezes

Eleotério

et al. 2012

Forensic Science International

View full text Add to dashboard Cite

A new voltammetric method for the determination of Δ(9)-tetrahydrocannabinol (Δ(9)-THC) is described. The voltammetric experiments were accomplished in N-N dimethylformamide/water (9:1, v/v), using tetrabutylammonium tetrafluoroborate (TBATFB) 0.1mol/L as supporting electrolyte and a glassy carbon disk electrode as the working electrode. The anodic peak current was observed at 0.0V (vs. Ag/AgCl) after a 30s pre-concentration step under an applied potential of -1.2V (vs. Ag/AgCl). A linear dependence of Δ(9)-THC detection was obtained in the concentration range 2.4-11.3ng/mL, with a linear correlation coefficient of 0.999 and a detection limit of 0.34ng/mL. The voltammetric method was used to measure the content of Δ(9)-THC in samples (hemp and hashish) confiscated by the police. The elimination of chemical interferences from the samples was promptly achieved through prior purification using the TLC technique, by employing methanol/water (4:1, v/v) as the mobile phase. The results showed excellent correlation with results attained by HPLC.

show abstract

“…38 This has included using cytochrome 39 P450, carbon nanotubes (CNTs) 40 , -cyclodextrin incorporated in polyaniline films with CNTs 41 , Schiff base films 42 , carbon paste electrodes modified with methoxy-substituted N-N'ethylenebis(salcylideneiminato)uranyl(VI) complexes and Pt disk electrodes modified with cobal thexacyanoferrate films. 43 However, the majority of these did not have the required sensitivity or specificity for widespread applications. To achieve this specificity, the main approach in recent work has been to incorporate either an aptamer or antibody specific or to use an alternative working electrode for cocaine detection.…”

Section: Chemical Detectionmentioning

confidence: 99%

Applications of electrochemical sensors: Forensic drug analysis

Shaw

Dennany

2017

Current Opinion in Electrochemistry

View full text Add to dashboard Cite

Electrochemical based sensors are a powerful analytical tool which can be exploited by the forensic community particularly for the analysis of illicit substances from street and biological samples. This report presents a brief overview on selected recent publications related to the application of electrochemical sensors to forensic drug analysis and gives opinions on the technical developments as well as the future applications in this field.

show abstract

Voltammetric determination of cocaine in confiscated samples using a cobalt hexacyanoferrate film-modified electrode

Cited by 54 publications

References 21 publications

Carbon nanotube β-cyclodextrin-modified electrode for quantification of cocaine in seized street samples

Carbon nanotube β-cyclodextrin-modified electrode for quantification of cocaine in seized street samples

Voltammetric determination of Δ9-THC in glassy carbon electrode: An important contribution to forensic electroanalysis

Applications of electrochemical sensors: Forensic drug analysis

Contact Info

Product

Resources

About