Voltammetric Anion Sensors based on Redox‐active Ferrocene‐bearing Macrocyclic Amides

Abstract

Reactions between 5‐ferrocenylisophthalic dichloride and 1,2‐bis(o‐aminophenoxy)ethane yield 1:1‐ and 2:2‐cyclization products with amide linkages, which are marked as L1 and L2, respectively. The crystal structure of the 2:2‐macrocycle L2 is determined by X‐ray single crystal structure analysis. Interestingly, L2 affords a folded conformation due to the intermolecular π–π interaction between two isophthaloyl groups, so as to stabilize the marcocylic conformation. The electrochemical anion sensing studies of L1 and L2 show that they have a good ability to recognize H2PO4–, and the 2:2‐cyclization products (L2) with two ferrocene groups, more anion binding sites, and larger cavities, give better electrochemical anion recognition results than L1.

Variables of the Analytical Electrochemical Data Acquisition for Boron Subphthalocyanines

“…Current responses associated with various analyte concentrations are useful for detection limit determination while scan rate modulation is important for kinetic studies. For example, this approach was taken for detecting quercetin, a natural therapeutic drug, via a modified glassy carbon electrode with titanium oxide and a Pt‐based porphyrin; [5] for quantifying L‐cysteine via a gold electrode modified with a peripherally alkanethiolated‐CoPc; [6] for sensing anionic pollutants using ferrocene‐containing macrocyclic amides; [7] and sensing industrially and environmentally relevant phenols with biosensors based on ITO and peripherally substituted boron subphthalocyanines (BsubPcs) [8] . In the latter case, improved responses were observed when using modified BsubPc‐electrodes with enzymes (phenyl oxidases), especially when the BsubPc molecule had 6 peripheral phenoxy groups (ie.…”