Voice quality after organ‐preservation therapy with definitive radiotherapy for laryngeal cancer

Lau, Valerie H.; Leonard, Rebecca J.; Goodrich, Susan; Luu, Quang; Farwell, D. Gregory; Lau, Derick H; Purdy, James A.; Chen, Allen M.

doi:10.1002/hed.21829

Cited by 8 publications

(1 citation statement)

References 50 publications

(30 reference statements)

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“…31 Preexisting comorbidities were recorded, and the Washington University Head and Neck Comorbidity Index was used to estimate the comorbidity score. 32,33 Time-to-event outcomes were estimated using the Kaplan-Meier method and compared using the log-rank test. Cox results are summarized as the hazard ratio (HR) and its 95% CI.…”

Section: Methodsmentioning

confidence: 99%

Oncologic and Functional Outcomes of Surgical and Nonsurgical Treatment of Advanced Squamous Cell Carcinoma of the Supraglottic Larynx

Elegbede

Rybicki

Adelstein

et al. 2015

JAMA Otolaryngol Head Neck Surg

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Section: Methodsmentioning

confidence: 99%

Oncologic and Functional Outcomes of Surgical and Nonsurgical Treatment of Advanced Squamous Cell Carcinoma of the Supraglottic Larynx

Elegbede

Rybicki

Adelstein

et al. 2015

JAMA Otolaryngol Head Neck Surg

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Telephonic voice intelligibility after laryngeal cancer treatment: is therapeutic approach significant?

Crosetti

Fantini

Arrigoni

et al. 2016

Eur Arch Otorhinolaryngol

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The aim was to investigate telephonic voice intelligibility in patients treated for laryngeal cancer using different approaches. In total, 90 patients treated for laryngeal cancer using different approaches and 12 healthy volunteers were recruited. Each patient and each healthy control read a list of words and sentences during a telephone call. Six auditors listened to each telephonic recording and transcribed the words and sentences they understood. Mean intelligibility rates for each treatment were assessed and compared. Regarding words, the poorest intelligibility was noted for type II open partial horizontal laryngectomies, followed by total laryngectomies. The best intelligibility was found for transoral laser microsurgery, followed by radiotherapy alone. For sentences, the poorest intelligibility was noted for type II open partial horizontal laryngectomies, followed by chemoradiotherapy. The best intelligibility was found for radiotherapy alone and transoral laser microsurgery. More aggressive surgery as well as chemoradiotherapy correlated with significantly poorer outcomes. Transoral laser microsurgery or radiotherapy alone ensured the best telephonic voice intelligibility. Intermediate-advanced T stages at diagnosis also showed significantly poorer intelligibility outcomes, suggesting that T stage represents an independent negative prognostic factor for voice intelligibility after treatment.

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Simulation study of high-dose-rate brachytherapy for early glottic cancer

et al. 2016

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Voice quality after organ‐preservation therapy with definitive radiotherapy for laryngeal cancer

Abstract: Despite the subtle differences in voice quality that existed, radiotherapy as a curative treatment for laryngeal cancer allows maintenance of a functional voice.

Cited by 8 publications

References 50 publications

Oncologic and Functional Outcomes of Surgical and Nonsurgical Treatment of Advanced Squamous Cell Carcinoma of the Supraglottic Larynx

Oncologic and Functional Outcomes of Surgical and Nonsurgical Treatment of Advanced Squamous Cell Carcinoma of the Supraglottic Larynx

Telephonic voice intelligibility after laryngeal cancer treatment: is therapeutic approach significant?

Simulation study of high-dose-rate brachytherapy for early glottic cancer

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