Voice Outcomes of Polyacrylamide Hydrogel Injection Laryngoplasty

Abstract

Based on the preliminary results of this trial, PAAG appears to be a long-lasting and safe injection material that is suitable for the treatment of glottal insufficiency caused by permanent unilateral vocal cord paralysis.

Cross-cultural Adaptation and Validation of the Voice Handicap Index Into Italian

“…These findings are in agreement with those reported in several studies. 6,17,[19][20][21][22][23][24][25][26][27][28][29][30] Journal of Voice, Vol. 24, No.…”

Utility and Safety of Commercially Available Injection Laryngoplasty Materials in a Rabbit Model

“…1,2 With advances in biotechnology, several excellent injection materials have become available, including Artecoll (20% [vol] polymethyl methacrylate (PMMA) microspheres + 80% [vol] bovine collagen; Rofil Medical International, Breda, The Netherlands); Radiesse (25% calcium hydroxyapatite + 75% carboxymethylcellulose; BioForm Medical Inc., San Mateo, CA); Aquamid (2.5% cross-linked polyacrylamide polymer and 97.5% water, Ferrosan A/S, Søborg, Denmark); and a hyaluronic acid derivative (Rofilan; Rofil Medical International, Breda, The Netherlands). [3][4][5][6] However, the only vocal fold injection material approved by the food and drug administrations of the United States and Korea is Radiesse. 7 Most vocal fold injection materials used today are approved as facial soft tissue fillers.…”

A 5-Year Assessment of Safety and Aesthetic Results after Facial Soft-Tissue Augmentation with Polyacrylamide Hydrogel (Aquamid): A Prospective Multicenter Study of 251 Patients

“…7 Indications have mainly been aesthetic, but the gel has also been used for reconstructive purposes. 9,10 To evaluate safety and efficacy of the material, the manufacturer initiated an originally 12-month, noncomparative, prospective clinical trial with 251 patients. 11 The study was extended for 24 months, 36/48 months, and finally 60 months.…”