Voice in female‐to‐male transsexual persons after long‐term androgen therapy

Cosyns, Marjan; Borsel, John Van; Wierckx, Katrien; Dedecker, David; Peer, Fleur Van de; Daelman, Tine; Laenen, Sofie; T’Sjoen, Guy

doi:10.1002/lary.24480

Cited by 98 publications

(60 citation statements)

References 25 publications

(61 reference statements)

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“…Small prospective studies exist which examine time to menstrual cessation with testosterone therapy [31,33]. Outcomes research on other transition related interventions, including speech therapy, are scattered throughout the literature [51,52,53]. Studies exist on patient satisfaction with surgical outcomes [54,55], but not on satisfaction with hormonal treatment outcomes separate from overall surveys of access to care or satisfaction with overall health care services in a given setting.…”

Section: Research To Datementioning

confidence: 99%

Priorities for transgender medical and healthcare research

Feldman

Brown

Deutsch

et al. 2016

Current Opinion in Endocrinology, Diabetes &Amp; Obesity

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121

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Purpose of Review Transgender individuals experience unique health disparities but are the subject of little focused health research. This manuscript reviews current literature on transgender medical and mental health outcomes and proposes research priorities to address knowledge gaps. Recent Findings Published research in transgender health care consists primarily of case reports, retrospective and cross-sectional studies, involving largely European settings. Challenges to US-based transgender health research include a diverse population where no single center has sufficient patient base to conduct clinical research with statistical rigor. Treatment regimens are heterogeneous and warrant study for best practices. Current research suggests increased mortality and depression in transgender individuals not receiving optimal care, and possibly a modest increase in cardiovascular risk related to hormone therapy. Current evidence does not support concerns for hormone related malignancy risk. Summary The priorities for transgender medical outcomes research should be to determine health disparities and co-morbid health conditions over the life span, along with the effects of mental health, medical, and surgical interventions on morbidity and mortality. Specific outcomes of interest based on frequency in the literature, potential severity of outcome, and patient-centered interest, include affective disorders, cardiovascular disease, malignancies, fertility, and time-dose related responses of specific interventions.

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Section: Research To Datementioning

confidence: 99%

Priorities for transgender medical and healthcare research

Feldman

Brown

Deutsch

et al. 2016

Current Opinion in Endocrinology, Diabetes &Amp; Obesity

Self Cite

121

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“…The virializing effect of testosterone is noticeable from a concentration of 150 ng/dL and higher. Repeated exposure to concentrations higher than 200 ng/dL results in irreversible changes; the voice of trans men cannot be distinguished acoustically from the voice of control men . In trans women, the lifetime absence of testosterone leads to some female voice characteristics.…”

Section: Introductionmentioning

confidence: 99%

Self‐perception of voice in transgender persons during cross‐sex hormone therapy

Bultynck¹,

Pas²,

Defreyne³

et al. 2017

The Laryngoscope

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“…It is known that the treatment with estrogen treatments do not promote satisfactory effects in the male larynx, that is, do not sufficiently increase f0 in transsexual women . A recent study examined the impact of hormone therapy on the f0 of a group of 38 transsexual men compared with a control group (cissexual or non‐transsexual men) and showed that only 10% of the transsexual men had difficulties with the decrease in f0. These difficulties, at least in part, seem to be associated with decreased sensitivity to androgens .…”

Section: Introductionmentioning

confidence: 99%

“…A recent study examined the impact of hormone therapy on the f0 of a group of 38 transsexual men compared with a control group (cissexual or non‐transsexual men) and showed that only 10% of the transsexual men had difficulties with the decrease in f0. These difficulties, at least in part, seem to be associated with decreased sensitivity to androgens . Thus, it was observed that the hormone therapy tends to be more efficient in cases of transsexual men than in transsexual women.…”

Section: Introductionmentioning

confidence: 99%