Vogesella perlucida-induced bacteremia in an advanced-age patient: first case report

Abstract

Background Vogesella species are common aquatic, Gram-negative rod-shaped bacteria, originally described in 1997. Vogesella perlucida was first isolated from spring water in 2008. Furthermore, bacterial pathogenicity of Vogesella perlucida has never been reported. Here, we report the first case of rare Vogesella perlucida-induced bacteremia in an advanced-age patient with many basic diseases and history of dexamethasone abuse. Case presentation A 71-year-old female was admitted with inflamed upper and lower limbs, rubefaction, pain and fever (about 40 °C). She had been injured in a fall at a vegetable market and then touched river snails with her injury hands. A few days later, soft tissue infection of the patient developed and worsened. Non-pigmented colonies were isolated from blood cultures of the patient. Initially, Vogesella perlucida was wrongly identified as Sphingomonas paucimobilis by Vitek-2 system with GN card. Besides, we failed to obtain an acceptable identification by the MALDI-TOF analysis. Finally, the isolated strain was identified as Vogesella perlucida by 16S rRNA gene sequences. In addition, the patient recovered well after a continuous treatment of levofloxacin for 12 days. Conclusion Traditional microbiological testing system may be inadequate in the diagnosis of rare pathogenic bacteria. Applications of molecular diagnostics techniques have great advantages in clinical microbiology laboratory. By using 16S rRNA gene sequence analysis, we report the the first case of rare Vogesella perlucida-induced bacteremia.

Unraveling the bacterial diversity of Cangar Hot Spring, Indonesia by Next Generation Sequencing of 16S rRNA gene

“…Recreational hot springs are known to harbor pathogens associated with human diseases such as Clostridium and Legionella strains (Chan et al 2015, Ghilamicael et al 2018. Our results suggested the occurrence of opportunistic pathogens causing bacteremia or the presence of bacteria in the human blood, such as Comamonas testosteroni (3.70%), Comamonas aquatica (3.54%), and Vogesella perlucida (0.59%) (Farooq et al 2017, Farshad et al 2012, Kaeuffer et al 2018, Tartar and Tartar 2020, Tiwari and Nanda 2019, Yu et al 2020. Furthermore, genus Blautia (3.21%) and Ruminococcus (2.86%), which are related to fecal contamination, were also observed (Devane et al 2020, Koskey et al 2014, Staley et al 2016).…”

The Gram-Negative Bacilli Isolated from Caves—Sphingomonas paucimobilis and Hafnia alvei and a Review of Their Involvement in Human Infections

“…In a recent study, Yu et al, using a 16S rRNA gene sequence analysis, demonstrated that a Vogesella perlucida isolate was misidentified as H. alvei by traditional microbiological testing [ 97 ]. The H. alvei isolate exhibits colistin resistance, which is unusual for an environmental isolate.…”

Vogesella urethralis-induced aspiration pneumonia and bacteremia in an elderly man: a first case report

“…Since then, several Vogesella species have been reported. Vogesella indigofera has been isolated from oxidation pond sediments, whereas others have been found in hot springs, river water, and in the rice rhizosphere, among others [2]. In addition, Vogesella urethralis has been isolated from the urine of a patient with chronic renal failure.…”

“…To date, only Vogesella perlucida has been reported as a pathogen in the genus Vogesella. However, Yu et al described a case of bacteremia in an elderly woman who had been taking dexamethasone for a long time, and bacteremia developed when she touched a pond snail with her wounded hand [2]. Vogesella, such as Pseudomonas, is assumed to cause opportunistic infections.…”

“…Several species of Vogesella have been subsequently discovered. However, Vogesella urethralis isolated from human urine was rst reported by Yu et al in 2020 [2]. Vogesella urethralis is a Gram-negative, rod-shaped, aerobic, motile, nonspore-forming, and poly-β-hydroxybutyrate-accumulating bacterium.…”