Abstract:Purpose. Cardiovascular fitness (maximal oxygen uptake [VO 2 max]) is linked with health indicators and the 2 subunit of the AMP-activated protein kinase (AMPK 2), encoded by the PRKAA2 gene, is an important metabolic sensor and can mediate part of exercise effect. It has been proposed that changes in the metabolic process bound with exercise might occur through epigenetic regulations. However, how VO 2 max can influence the epigenetic mechanism and consequently health is still unknown. the aim of this study w… Show more
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